Compile Data Set for Download or QSAR
Found 10 Enz. Inhib. hit(s) with Target = 'Carbonic anhydrase 1' and Ligand = 'BDBM10875'
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10875(5-(2-chlorophenyl)-1,3,4-thiadiazole-2-sulfonamide...)copy SMILEScopy InChI
Affinity DataKi:  690nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2TQBPubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10875(5-(2-chlorophenyl)-1,3,4-thiadiazole-2-sulfonamide...)copy SMILEScopy InChI
Affinity DataKi:  690nMAssay Description:Inhibition of recombinant human carbonic anhydrase-1 by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB83QGPubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10875(5-(2-chlorophenyl)-1,3,4-thiadiazole-2-sulfonamide...)copy SMILEScopy InChI
Affinity DataKi:  690nMpH: 7.5Assay Description:Inhibition of human carbonic anhydrase I by spectrophotometry at pH 7.5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53M44PubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10875(5-(2-chlorophenyl)-1,3,4-thiadiazole-2-sulfonamide...)copy SMILEScopy InChI
Affinity DataKi:  690nMpH: 7.5Assay Description:Inhibition of human recombinant carbonic anhydrase 1 at pH 7.5 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6JRWPubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10875(5-(2-chlorophenyl)-1,3,4-thiadiazole-2-sulfonamide...)copy SMILEScopy InChI
Affinity DataKi:  690nMAssay Description:Inhibition of human recombinant CA1 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB53WWPubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10875(5-(2-chlorophenyl)-1,3,4-thiadiazole-2-sulfonamide...)copy SMILEScopy InChI
Affinity DataKi:  690nMAssay Description:Ki value against human carbonic anhydrase I (hCA I)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29887RZPubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10875(5-(2-chlorophenyl)-1,3,4-thiadiazole-2-sulfonamide...)copy SMILEScopy InChI
Affinity DataKi:  690nMAssay Description:Inhibition of human recombinant CA1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM598PPubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10875(5-(2-chlorophenyl)-1,3,4-thiadiazole-2-sulfonamide...)copy SMILEScopy InChI
Affinity DataKi:  690nMAssay Description:Ki value against human carbonic anhydrase IMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7H1NPubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10875(5-(2-chlorophenyl)-1,3,4-thiadiazole-2-sulfonamide...)copy SMILEScopy InChI
Affinity DataKi:  690nMAssay Description:Inhibition of human recombinant cytosolic isozyme CA I by stopped-flow CO2 hydrase methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5NNHPubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10875(5-(2-chlorophenyl)-1,3,4-thiadiazole-2-sulfonamide...)copy SMILEScopy InChI
Affinity DataKi:  690nMAssay Description:Inhibition of human recombinant carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5P89PubMed