Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Carbonic anhydrase 1' and Ligand = 'BDBM222057'
TargetCarbonic anhydrase 1(Homo sapiens (Human))TBA
LigandPNGBDBM222057((3aR,4S,7R,7aS)-2-(4-((E)-3-(furan-2-yl)acryloyl)p...)copy SMILEScopy InChI
Affinity DataKi:  0.405nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N852GPubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))TBA
LigandPNGBDBM222057((3aR,4S,7R,7aS)-2-(4-((E)-3-(furan-2-yl)acryloyl)p...)copy SMILEScopy InChI
Affinity DataKi:  0.595nM ΔG°:  -52.7kJ/mole IC50: 0.655nMpH: 7.4 T: 2°CAssay Description:Esterase activity assay was performed based on the method of by Verpoorte et al. [Verpoorte et al., J. Biol. Chem., 242:4221-4229] as described in pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9NZBPubMed