Compile Data Set for Download or QSAR
Found 22 Enz. Inhib. hit(s) with Target = 'Carbonic anhydrase 1' and Ligand = 'BDBM50013792'
TargetCarbonic anhydrase 1(Homo sapiens (Human))
ENSCM/UMII/UMR-CNRS 5635

Curated by ChEMBL
LigandPNGBDBM50013792(CHEBI:6822 | METHAZOLAMIDE | Neptazane)copy SMILEScopy InChI
Affinity DataKi:  14nMAssay Description:Inhibition of human carbonic anhydrase 1-catalyzed CO2 hydration preincubated for 10 mins by stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27D2WPDPubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
ENSCM/UMII/UMR-CNRS 5635

Curated by ChEMBL
LigandPNGBDBM50013792(CHEBI:6822 | METHAZOLAMIDE | Neptazane)copy SMILEScopy InChI
Affinity DataKi:  50nMAssay Description:Inhibition of recombinant human carbonic anhydrase 1 assessed as reduction in CO2 hydration preincubated for 15 mins followed by CO2 addition measure...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN97XSPubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
ENSCM/UMII/UMR-CNRS 5635

Curated by ChEMBL
LigandPNGBDBM50013792(CHEBI:6822 | METHAZOLAMIDE | Neptazane)copy SMILEScopy InChI
Affinity DataKi:  50nMAssay Description:Inhibition of full length human cytosolic carbonic anhydrase 1 preincubated for 15 mins by stop flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70K9RPubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
ENSCM/UMII/UMR-CNRS 5635

Curated by ChEMBL
LigandPNGBDBM50013792(CHEBI:6822 | METHAZOLAMIDE | Neptazane)copy SMILEScopy InChI
Affinity DataKi:  50nMAssay Description:Inhibition of full length human CA 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C218GPubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
ENSCM/UMII/UMR-CNRS 5635

Curated by ChEMBL
LigandPNGBDBM50013792(CHEBI:6822 | METHAZOLAMIDE | Neptazane)copy SMILEScopy InChI
Affinity DataKi:  50nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 1 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47S3JPubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
ENSCM/UMII/UMR-CNRS 5635

Curated by ChEMBL
LigandPNGBDBM50013792(CHEBI:6822 | METHAZOLAMIDE | Neptazane)copy SMILEScopy InChI
Affinity DataKi:  50nMAssay Description:Inhibition of human carbonic anhydrase-1 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K7GPubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
ENSCM/UMII/UMR-CNRS 5635

Curated by ChEMBL
LigandPNGBDBM50013792(CHEBI:6822 | METHAZOLAMIDE | Neptazane)copy SMILEScopy InChI
Affinity DataKi:  50nMAssay Description:Inhibition of human recombinant carbonic anhydrase 1 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K2B62PubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
ENSCM/UMII/UMR-CNRS 5635

Curated by ChEMBL
LigandPNGBDBM50013792(CHEBI:6822 | METHAZOLAMIDE | Neptazane)copy SMILEScopy InChI
Affinity DataKi:  50nMAssay Description:Inhibition of human recombinant Carbonic anhydrase 2 compound preincubated for 15 mins by stopped flow CO2 hydrase assay methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959K68PubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
ENSCM/UMII/UMR-CNRS 5635

Curated by ChEMBL
LigandPNGBDBM50013792(CHEBI:6822 | METHAZOLAMIDE | Neptazane)copy SMILEScopy InChI
Affinity DataKi:  50nMAssay Description:Inhibition of human recombinant carbonic anhydrase 1 by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3T9XPubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
ENSCM/UMII/UMR-CNRS 5635

Curated by ChEMBL
LigandPNGBDBM50013792(CHEBI:6822 | METHAZOLAMIDE | Neptazane)copy SMILEScopy InChI
Affinity DataKi:  50nMAssay Description:Inhibition of human carbonic anhydrase 1 pre-incubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3H2MPubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
ENSCM/UMII/UMR-CNRS 5635

Curated by ChEMBL
LigandPNGBDBM50013792(CHEBI:6822 | METHAZOLAMIDE | Neptazane)copy SMILEScopy InChI
Affinity DataKi:  50nMAssay Description:Inhibition of recombinant human carbonic anhydrase-1 by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB83QGPubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
ENSCM/UMII/UMR-CNRS 5635

Curated by ChEMBL
LigandPNGBDBM50013792(CHEBI:6822 | METHAZOLAMIDE | Neptazane)copy SMILEScopy InChI
Affinity DataKi:  50nMAssay Description:Inhibition of human Carbonic anhydrase1 using CO2 as substrate preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9CXHPubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
ENSCM/UMII/UMR-CNRS 5635

Curated by ChEMBL
LigandPNGBDBM50013792(CHEBI:6822 | METHAZOLAMIDE | Neptazane)copy SMILEScopy InChI
Affinity DataKi:  50nMAssay Description:Inhibition of human carbonic anhydrase 1 incubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM896MPubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
ENSCM/UMII/UMR-CNRS 5635

Curated by ChEMBL
LigandPNGBDBM50013792(CHEBI:6822 | METHAZOLAMIDE | Neptazane)copy SMILEScopy InChI
Affinity DataKi:  50nMAssay Description:Inhibition of full length human cytosolic carbonic anhydrase 1 preincubated for 15 mins by stop flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70K9RPubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
ENSCM/UMII/UMR-CNRS 5635

Curated by ChEMBL
LigandPNGBDBM50013792(CHEBI:6822 | METHAZOLAMIDE | Neptazane)copy SMILEScopy InChI
Affinity DataKi:  50nMAssay Description:Inhibition of human carbonic anhydrase-1 assessed as reduction in CO2 hydration preincubated for 15 mins followed by CO2 addition measured for 10 to ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z75PZPubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
ENSCM/UMII/UMR-CNRS 5635

Curated by ChEMBL
LigandPNGBDBM50013792(CHEBI:6822 | METHAZOLAMIDE | Neptazane)copy SMILEScopy InChI
Affinity DataKi:  50nMAssay Description:Inhibition of human CA1 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93BJFPubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
ENSCM/UMII/UMR-CNRS 5635

Curated by ChEMBL
LigandPNGBDBM50013792(CHEBI:6822 | METHAZOLAMIDE | Neptazane)copy SMILEScopy InChI
Affinity DataKi:  50nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 1 preincubated for 15 mins at room temperature followed by 72 hrs at 4 degC by stopped flow CO2 hydr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q5026PubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
ENSCM/UMII/UMR-CNRS 5635

Curated by ChEMBL
LigandPNGBDBM50013792(CHEBI:6822 | METHAZOLAMIDE | Neptazane)copy SMILEScopy InChI
Affinity DataKi:  50nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3QGVPubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
ENSCM/UMII/UMR-CNRS 5635

Curated by ChEMBL
LigandPNGBDBM50013792(CHEBI:6822 | METHAZOLAMIDE | Neptazane)copy SMILEScopy InChI
Affinity DataKi:  780nMAssay Description:Inhibition of human carbonic anhydrase 1 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2RW2PubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
ENSCM/UMII/UMR-CNRS 5635

Curated by ChEMBL
LigandPNGBDBM50013792(CHEBI:6822 | METHAZOLAMIDE | Neptazane)copy SMILEScopy InChI
Affinity DataKi:  780nMAssay Description:Inhibition of recombinant human full-length carbonic anhydrase 1 preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5K8PPubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
ENSCM/UMII/UMR-CNRS 5635

Curated by ChEMBL
LigandPNGBDBM50013792(CHEBI:6822 | METHAZOLAMIDE | Neptazane)copy SMILEScopy InChI
Affinity DataKi:  780nMAssay Description:Inhibition of human CA1 cytosolic isoform after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2086890PubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
ENSCM/UMII/UMR-CNRS 5635

Curated by ChEMBL
LigandPNGBDBM50013792(CHEBI:6822 | METHAZOLAMIDE | Neptazane)copy SMILEScopy InChI
Affinity DataKi:  780nMAssay Description:Inhibition of human cloned cytosolic carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63PH6PubMed