Compile Data Set for Download or QSAR
Found 9 Enz. Inhib. hit(s) with Target = 'Carbonic anhydrase 1' and Ligand = 'BDBM50308986'
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Dumlupinar University

LigandPNGBDBM50308986(2,4-Dichloro-5-sulphamoylbenzoate (2) | CHEMBL5908...)copy SMILEScopy InChI
Affinity DataIC50: 130nMpH: 7.4Assay Description:The carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of the 4-nitrophenylacetate (NPA) to the 4-nitrophenylate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PC318RPubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Dumlupinar University

LigandPNGBDBM50308986(2,4-Dichloro-5-sulphamoylbenzoate (2) | CHEMBL5908...)copy SMILEScopy InChI
Affinity DataIC50: 137nMAssay Description:The method for determination of the Ki values is described elsewhere [Landolfi et al., J. Pharmacol. Toxicol. Methods, 38:169-172; Bülbül et al., J. ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PC318RPubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Dumlupinar University

LigandPNGBDBM50308986(2,4-Dichloro-5-sulphamoylbenzoate (2) | CHEMBL5908...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:The carbonic anhydrase activity was assayed by following the hydration of CO2 according to the method described by Wilbur and Anderson [Wilbur et al....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PC318RPubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Dumlupinar University

LigandPNGBDBM50308986(2,4-Dichloro-5-sulphamoylbenzoate (2) | CHEMBL5908...)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Inhibition of CA1 from human erythrocytes by Lineweaver-Burke analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9XK3PubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Dumlupinar University

LigandPNGBDBM50308986(2,4-Dichloro-5-sulphamoylbenzoate (2) | CHEMBL5908...)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:Inhibition of hydratase-activity of CA1 from human erythrocytes by CO2-hydration methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9XK3PubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Dumlupinar University

LigandPNGBDBM50308986(2,4-Dichloro-5-sulphamoylbenzoate (2) | CHEMBL5908...)copy SMILEScopy InChI
Affinity DataIC50: 320nMAssay Description:Inhibition of esterase-activity of CA1 from human erythrocytes by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9XK3PubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Dumlupinar University

LigandPNGBDBM50308986(2,4-Dichloro-5-sulphamoylbenzoate (2) | CHEMBL5908...)copy SMILEScopy InChI
Affinity DataIC50: 320nMAssay Description:The carbonic anhydrase activity was assayed by following the hydration of CO2 according to the method described by Wilbur and Anderson [Wilbur et al....More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PC318RPubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Dumlupinar University

LigandPNGBDBM50308986(2,4-Dichloro-5-sulphamoylbenzoate (2) | CHEMBL5908...)copy SMILEScopy InChI
Affinity DataIC50: 800nMpH: 7.4Assay Description:The carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of the 4-nitrophenylacetate (NPA) to the 4-nitrophenylate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PC318RPubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Dumlupinar University

LigandPNGBDBM50308986(2,4-Dichloro-5-sulphamoylbenzoate (2) | CHEMBL5908...)copy SMILEScopy InChI
Affinity DataIC50: 990nMAssay Description:The method for determination of the Ki values is described elsewhere [Landolfi et al., J. Pharmacol. Toxicol. Methods, 38:169-172; Bülbül et al., J. ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PC318RPubMed