Compile Data Set for Download or QSAR
Found 5 Enz. Inhib. hit(s) with Target = 'Carbonic anhydrase 1' and Ligand = 'BDBM50329832'
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Vilnius University

LigandPNGBDBM50329832(5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...)copy SMILEScopy InChI
Affinity DataKd:  1.11E+4nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0MMKPubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Vilnius University

LigandPNGBDBM50329832(5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...)copy SMILEScopy InChI
Affinity DataKd:  4.80E+3nMAssay Description:Binding affinity to human recombinant CA1 expressed in Escherichia coli by fluorescence-based thermal shift assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571DWKPubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Vilnius University

LigandPNGBDBM50329832(5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...)copy SMILEScopy InChI
Affinity DataKd:  1.11E+4nMAssay Description:Binding affinity to recombinant human N-terminal His6-tagged carbonic anhydrase 1 (3 to 261 residues) expressed in Escherichia coli BL21 (DE3) in pre...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H997S0PubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Vilnius University

LigandPNGBDBM50329832(5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...)copy SMILEScopy InChI
Affinity DataKd:  161nMAssay Description:Binding affinity to recombinant human N-terminal His6-tagged carbonic anhydrase 1 (3 to 261 residues) expressed in Escherichia coli BL21 (DE3) assess...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H997S0PubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Vilnius University

LigandPNGBDBM50329832(5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulf...)copy SMILEScopy InChI
Affinity DataKd:  1.10E+4nMAssay Description:Binding affinity to human recombinant carbonic anhydrase 1 by thermal shift assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5F6HPubMed