Compile Data Set for Download or QSAR
Found 30 Enz. Inhib. hit(s) with Target = 'Carbonic anhydrase 2' and Ligand = 'BDBM10855'
TargetCarbonic anhydrase 2(Homo sapiens (Human))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM10855(2-aminobenzene-1-sulfonamide | CHEMBL6705 | US1017...)copy SMILEScopy InChI
Affinity DataKi:  0.00300nMAssay Description:Inhibition of human CA2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z761VPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM10855(2-aminobenzene-1-sulfonamide | CHEMBL6705 | US1017...)copy SMILEScopy InChI
Affinity DataKi:  295nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X275CPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM10855(2-aminobenzene-1-sulfonamide | CHEMBL6705 | US1017...)copy SMILEScopy InChI
Affinity DataKi:  295nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ3463PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM10855(2-aminobenzene-1-sulfonamide | CHEMBL6705 | US1017...)copy SMILEScopy InChI
Affinity DataKi:  295nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2TQBPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM10855(2-aminobenzene-1-sulfonamide | CHEMBL6705 | US1017...)copy SMILEScopy InChI
Affinity DataKi:  295nM ΔG°:  -37.3kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2902200PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM10855(2-aminobenzene-1-sulfonamide | CHEMBL6705 | US1017...)copy SMILEScopy InChI
Affinity DataKi:  295nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins measured for 10 to 100 sec by stopped-flow methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9D4XPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM10855(2-aminobenzene-1-sulfonamide | CHEMBL6705 | US1017...)copy SMILEScopy InChI
Affinity DataKi:  295nMAssay Description:Inhibition of human recombinant CA2 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB53WWPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM10855(2-aminobenzene-1-sulfonamide | CHEMBL6705 | US1017...)copy SMILEScopy InChI
Affinity DataKi:  295nMAssay Description:Inhibitory activity against human carbonic anhydrase II (CA2)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22806T7PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM10855(2-aminobenzene-1-sulfonamide | CHEMBL6705 | US1017...)copy SMILEScopy InChI
Affinity DataKi:  295nMAssay Description:Inhibition of recombinant human carbonic anhydrase-2 by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB83QGPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM10855(2-aminobenzene-1-sulfonamide | CHEMBL6705 | US1017...)copy SMILEScopy InChI
Affinity DataKi:  295nMAssay Description:Inhibition of human recombinant CA2 by stopped-flow CO2 hydration assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5T7KPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM10855(2-aminobenzene-1-sulfonamide | CHEMBL6705 | US1017...)copy SMILEScopy InChI
Affinity DataKi:  295nMpH: 7.5Assay Description:Inhibition of human carbonic anhydrase II by spectrophotometry at pH 7.5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53M44PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM10855(2-aminobenzene-1-sulfonamide | CHEMBL6705 | US1017...)copy SMILEScopy InChI
Affinity DataKi:  295nMpH: 7.5Assay Description:Inhibition of human recombinant carbonic anhydrase 2 at pH 7.5 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6JRWPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM10855(2-aminobenzene-1-sulfonamide | CHEMBL6705 | US1017...)copy SMILEScopy InChI
Affinity DataKi:  295nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5P89PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM10855(2-aminobenzene-1-sulfonamide | CHEMBL6705 | US1017...)copy SMILEScopy InChI
Affinity DataKi:  295nMAssay Description:Inhibition of human carbonic anhydrase II (hCA II)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WW7J6MPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM10855(2-aminobenzene-1-sulfonamide | CHEMBL6705 | US1017...)copy SMILEScopy InChI
Affinity DataKi:  295nMAssay Description:Inhibition of human carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6KXVPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM10855(2-aminobenzene-1-sulfonamide | CHEMBL6705 | US1017...)copy SMILEScopy InChI
Affinity DataKi:  295nMAssay Description:Inhibition of cloned isozyme, human carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5GJQPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM10855(2-aminobenzene-1-sulfonamide | CHEMBL6705 | US1017...)copy SMILEScopy InChI
Affinity DataKi:  295nMAssay Description:Inhibitory activity against human carbonic anhydrase II (hCA II) by using esterase assay methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7VJ8PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM10855(2-aminobenzene-1-sulfonamide | CHEMBL6705 | US1017...)copy SMILEScopy InChI
Affinity DataKi:  295nMAssay Description:Inhibitory activity against human recombinant carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67HMKPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM10855(2-aminobenzene-1-sulfonamide | CHEMBL6705 | US1017...)copy SMILEScopy InChI
Affinity DataKi:  295nMAssay Description:Inhibitory activity against human recombinant carbonic anhydrase II (CA2)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1XXCPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM10855(2-aminobenzene-1-sulfonamide | CHEMBL6705 | US1017...)copy SMILEScopy InChI
Affinity DataKi:  295nMAssay Description:Inhibitory activity against Human carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N29XN9PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM10855(2-aminobenzene-1-sulfonamide | CHEMBL6705 | US1017...)copy SMILEScopy InChI
Affinity DataKi:  295nMAssay Description:Ki value against human carbonic anhydrase II (hCA II)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29887RZPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM10855(2-aminobenzene-1-sulfonamide | CHEMBL6705 | US1017...)copy SMILEScopy InChI
Affinity DataKi:  295nMAssay Description:Inhibition of human recombinant CA2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM598PPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM10855(2-aminobenzene-1-sulfonamide | CHEMBL6705 | US1017...)copy SMILEScopy InChI
Affinity DataKi:  295nMAssay Description:Ki value against human carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7H1NPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM10855(2-aminobenzene-1-sulfonamide | CHEMBL6705 | US1017...)copy SMILEScopy InChI
Affinity DataKi:  295nMAssay Description:Inhibition of human recombinant cytosolic isozyme CA II by stopped-flow CO2 hydrase methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5NNHPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM10855(2-aminobenzene-1-sulfonamide | CHEMBL6705 | US1017...)copy SMILEScopy InChI
Affinity DataKi:  295nMAssay Description:Inhibition of human carbonic anhydrase II (CAII)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2668GC9PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM10855(2-aminobenzene-1-sulfonamide | CHEMBL6705 | US1017...)copy SMILEScopy InChI
Affinity DataKi:  295nMAssay Description:Inhibition of human recombinant CA2 by stopped-flow CO2 assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2HQJPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM10855(2-aminobenzene-1-sulfonamide | CHEMBL6705 | US1017...)copy SMILEScopy InChI
Affinity DataKi:  295nMAssay Description:Inhibition of human recombinant CA2 by stopped-flow hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6D4SPubMed
TargetCarbonic anhydrase 2(Mycobacterium tuberculosis)
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM10855(2-aminobenzene-1-sulfonamide | CHEMBL6705 | US1017...)copy SMILEScopy InChI
Affinity DataKi:  3.37E+4nMAssay Description:Inhibition of full length Mycobacterium tuberculosis H37Rv recombinant carbonic anhydrase 2 encoded by RV3588c by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6D4SPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM10855(2-aminobenzene-1-sulfonamide | CHEMBL6705 | US1017...)copy SMILEScopy InChI
Affinity DataKi:  3.38E+6nMAssay Description:Inhibition of human carbonic anhydrase 2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9XGRPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM10855(2-aminobenzene-1-sulfonamide | CHEMBL6705 | US1017...)copy SMILEScopy InChI
Affinity DataIC50: 2.64E+3nMAssay Description:Inhibitory concentration against human cystolic isozyme II of Carbonic anhydraseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N22VWPubMed