Compile Data Set for Download or QSAR
Found 33 Enz. Inhib. hit(s) with Target = 'Carbonic anhydrase 2' and Ligand = 'BDBM26995'
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Centre Scientifique de Monaco

Curated by ChEMBL
LigandPNGBDBM26995(CHEMBL355001 | H2NSO2NH2 | sulfamamide | sulfamide...)copy SMILEScopy InChI
Affinity DataKi:  1.13nMAssay Description:Inhibition of human recombinant CA2 by stopped-flow CO2 hydration assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5T7KPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Centre Scientifique de Monaco

Curated by ChEMBL
LigandPNGBDBM26995(CHEMBL355001 | H2NSO2NH2 | sulfamamide | sulfamide...)copy SMILEScopy InChI
Affinity DataKi:  8.20E+4nMAssay Description:Inhibitory activity against human cloned carbonic anhydrase II (hCA II)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BK1CW5PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Centre Scientifique de Monaco

Curated by ChEMBL
LigandPNGBDBM26995(CHEMBL355001 | H2NSO2NH2 | sulfamamide | sulfamide...)copy SMILEScopy InChI
Affinity DataKi:  8.20E+4nMAssay Description:Inhibitory activity against human cloned isoenzyme carbonic anhydrase II (hCA II), by esterase method.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GB24MWPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Centre Scientifique de Monaco

Curated by ChEMBL
LigandPNGBDBM26995(CHEMBL355001 | H2NSO2NH2 | sulfamamide | sulfamide...)copy SMILEScopy InChI
Affinity DataKi:  1.13E+6nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28054D1PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Centre Scientifique de Monaco

Curated by ChEMBL
LigandPNGBDBM26995(CHEMBL355001 | H2NSO2NH2 | sulfamamide | sulfamide...)copy SMILEScopy InChI
Affinity DataKi:  1.13E+6nMAssay Description:Inhibition of human recombinant CA2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29886PNPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Centre Scientifique de Monaco

Curated by ChEMBL
LigandPNGBDBM26995(CHEMBL355001 | H2NSO2NH2 | sulfamamide | sulfamide...)copy SMILEScopy InChI
Affinity DataKi:  1.13E+6nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348N4MPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Centre Scientifique de Monaco

Curated by ChEMBL
LigandPNGBDBM26995(CHEMBL355001 | H2NSO2NH2 | sulfamamide | sulfamide...)copy SMILEScopy InChI
Affinity DataKi:  1.13E+6nMAssay Description:Inhibition of human carbonic anhydrase-2 by CO2 hydration reaction based colorimetric stopped-flow methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8FK8PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Centre Scientifique de Monaco

Curated by ChEMBL
LigandPNGBDBM26995(CHEMBL355001 | H2NSO2NH2 | sulfamamide | sulfamide...)copy SMILEScopy InChI
Affinity DataKi:  1.13E+6nMAssay Description:Inhibition of human carbonic anhydrase 2 by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5SV7PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Centre Scientifique de Monaco

Curated by ChEMBL
LigandPNGBDBM26995(CHEMBL355001 | H2NSO2NH2 | sulfamamide | sulfamide...)copy SMILEScopy InChI
Affinity DataKi:  1.13E+6nMAssay Description:Inhibition of human carbonic anhydrase 2 measured by CO2 hydration reaction assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50MT8PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Centre Scientifique de Monaco

Curated by ChEMBL
LigandPNGBDBM26995(CHEMBL355001 | H2NSO2NH2 | sulfamamide | sulfamide...)copy SMILEScopy InChI
Affinity DataKi:  1.13E+6nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95C24PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Centre Scientifique de Monaco

Curated by ChEMBL
LigandPNGBDBM26995(CHEMBL355001 | H2NSO2NH2 | sulfamamide | sulfamide...)copy SMILEScopy InChI
Affinity DataKi:  1.13E+6nMpH: 7.5Assay Description:Inhibition of human carbonic anhydrase 2 after 15 mins by CO2 hydrase assay at pH 7.5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN672RPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Centre Scientifique de Monaco

Curated by ChEMBL
LigandPNGBDBM26995(CHEMBL355001 | H2NSO2NH2 | sulfamamide | sulfamide...)copy SMILEScopy InChI
Affinity DataKi:  1.13E+6nMpH: 8.3Assay Description:Inhibition of recombinant human carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assay at pH 8.3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930TGNPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Centre Scientifique de Monaco

Curated by ChEMBL
LigandPNGBDBM26995(CHEMBL355001 | H2NSO2NH2 | sulfamamide | sulfamide...)copy SMILEScopy InChI
Affinity DataKi:  1.13E+6nMAssay Description:Inhibitory activity against human Carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3SDVPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Centre Scientifique de Monaco

Curated by ChEMBL
LigandPNGBDBM26995(CHEMBL355001 | H2NSO2NH2 | sulfamamide | sulfamide...)copy SMILEScopy InChI
Affinity DataKi:  1.13E+6nMAssay Description:Inhibitory constant against carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H995ZDPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Centre Scientifique de Monaco

Curated by ChEMBL
LigandPNGBDBM26995(CHEMBL355001 | H2NSO2NH2 | sulfamamide | sulfamide...)copy SMILEScopy InChI
Affinity DataKi:  1.13E+6nMAssay Description:Inhibitory activity against human carbonic anhydrase II expressed in Escherichia coliChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN09QFPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Centre Scientifique de Monaco

Curated by ChEMBL
LigandPNGBDBM26995(CHEMBL355001 | H2NSO2NH2 | sulfamamide | sulfamide...)copy SMILEScopy InChI
Affinity DataKi:  1.13E+6nMAssay Description:Inhibition constant against human carbonic anhydrase isozyme hCA IIMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X58JJPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Centre Scientifique de Monaco

Curated by ChEMBL
LigandPNGBDBM26995(CHEMBL355001 | H2NSO2NH2 | sulfamamide | sulfamide...)copy SMILEScopy InChI
Affinity DataKi:  1.13E+6nMAssay Description:Inhibition of human CA2 after 15 mins by stopped-flow/Co2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD4ZJ0PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Centre Scientifique de Monaco

Curated by ChEMBL
LigandPNGBDBM26995(CHEMBL355001 | H2NSO2NH2 | sulfamamide | sulfamide...)copy SMILEScopy InChI
Affinity DataKi:  1.13E+6nMAssay Description:Inhibition of human carbonic anhydrase-2 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5WXCPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Centre Scientifique de Monaco

Curated by ChEMBL
LigandPNGBDBM26995(CHEMBL355001 | H2NSO2NH2 | sulfamamide | sulfamide...)copy SMILEScopy InChI
Affinity DataKi:  1.13E+6nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W79PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Centre Scientifique de Monaco

Curated by ChEMBL
LigandPNGBDBM26995(CHEMBL355001 | H2NSO2NH2 | sulfamamide | sulfamide...)copy SMILEScopy InChI
Affinity DataKi:  1.13E+6nM ΔG°:  -16.5kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition of Helicobacter pylori alpha carbonic anhydrase preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W9583BPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Centre Scientifique de Monaco

Curated by ChEMBL
LigandPNGBDBM26995(CHEMBL355001 | H2NSO2NH2 | sulfamamide | sulfamide...)copy SMILEScopy InChI
Affinity DataKi:  1.13E+6nMAssay Description:Inhibitory constant against human Carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9CJWPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Centre Scientifique de Monaco

Curated by ChEMBL
LigandPNGBDBM26995(CHEMBL355001 | H2NSO2NH2 | sulfamamide | sulfamide...)copy SMILEScopy InChI
Affinity DataKi:  1.13E+6nMAssay Description:Inhibition of human cytosolic carbonic anhydrase-2 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8806PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Centre Scientifique de Monaco

Curated by ChEMBL
LigandPNGBDBM26995(CHEMBL355001 | H2NSO2NH2 | sulfamamide | sulfamide...)copy SMILEScopy InChI
Affinity DataKi:  1.13E+6nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD70TXPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Centre Scientifique de Monaco

Curated by ChEMBL
LigandPNGBDBM26995(CHEMBL355001 | H2NSO2NH2 | sulfamamide | sulfamide...)copy SMILEScopy InChI
Affinity DataKi:  1.13E+6nMAssay Description:Inhibition of human recombinant wild type CA2 by stopped-flow CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZC846GPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Centre Scientifique de Monaco

Curated by ChEMBL
LigandPNGBDBM26995(CHEMBL355001 | H2NSO2NH2 | sulfamamide | sulfamide...)copy SMILEScopy InChI
Affinity DataKi:  1.13E+6nMAssay Description:Inhibition of human erythrocytes esterase activity of carbonic anhydrase-2 using 4-nitrophenylacetate as substrate after 3 mins by Lineweaver-Burk pl...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35W0KPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Centre Scientifique de Monaco

Curated by ChEMBL
LigandPNGBDBM26995(CHEMBL355001 | H2NSO2NH2 | sulfamamide | sulfamide...)copy SMILEScopy InChI
Affinity DataKi:  1.13E+6nMAssay Description:Inhibition of full length human carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9K7QPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Centre Scientifique de Monaco

Curated by ChEMBL
LigandPNGBDBM26995(CHEMBL355001 | H2NSO2NH2 | sulfamamide | sulfamide...)copy SMILEScopy InChI
Affinity DataKi:  1.13E+6nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 assessed as inhibition of CO2 hydration preincubated for 15 mins by Lineweaver-burk plot methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M047FFPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Centre Scientifique de Monaco

Curated by ChEMBL
LigandPNGBDBM26995(CHEMBL355001 | H2NSO2NH2 | sulfamamide | sulfamide...)copy SMILEScopy InChI
Affinity DataKi:  1.13E+6nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 assessed as inhibition of CO2 hydration incubated for 15 mins prior to testing by stopped flow C...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD5012PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Centre Scientifique de Monaco

Curated by ChEMBL
LigandPNGBDBM26995(CHEMBL355001 | H2NSO2NH2 | sulfamamide | sulfamide...)copy SMILEScopy InChI
Affinity DataKi:  1.13E+6nMAssay Description:Inhibition of human CA2 incubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028V0PPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Centre Scientifique de Monaco

Curated by ChEMBL
LigandPNGBDBM26995(CHEMBL355001 | H2NSO2NH2 | sulfamamide | sulfamide...)copy SMILEScopy InChI
Affinity DataKi:  1.13E+6nMAssay Description:Inhibition of human carbonic anhydrase 2 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7DDZPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Centre Scientifique de Monaco

Curated by ChEMBL
LigandPNGBDBM26995(CHEMBL355001 | H2NSO2NH2 | sulfamamide | sulfamide...)copy SMILEScopy InChI
Affinity DataKi:  1.13E+6nMAssay Description:Inhibition of human CA2 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93BJFPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Centre Scientifique de Monaco

Curated by ChEMBL
LigandPNGBDBM26995(CHEMBL355001 | H2NSO2NH2 | sulfamamide | sulfamide...)copy SMILEScopy InChI
Affinity DataKi:  1.13E+6nMAssay Description:Inhibition of human carbonic anhydrase-2 at 20 degC preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4SV8PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Centre Scientifique de Monaco

Curated by ChEMBL
LigandPNGBDBM26995(CHEMBL355001 | H2NSO2NH2 | sulfamamide | sulfamide...)copy SMILEScopy InChI
Affinity DataKi:  1.13E+9nMAssay Description:Inhibitory activity against human carbonic anhydrase II at 0.01 uMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X87D5PubMed