Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Carbonic anhydrase 2' and Ligand = 'BDBM4374'
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM4374((2E)-3-(4-hydroxyphenyl)prop-2-enoic acid | (2E)-3...)copy SMILEScopy InChI
Affinity DataKi:  980nMAssay Description:Inhibition of human CA2 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6ZP1PubMed
TargetCarbonic anhydrase 2(Mycobacterium tuberculosis)
Università degli Studi di Firenze

LigandPNGBDBM4374((2E)-3-(4-hydroxyphenyl)prop-2-enoic acid | (2E)-3...)copy SMILEScopy InChI
Affinity DataKi:  1.56E+3nM ΔG°:  -33.1kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RF5SZWPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM4374((2E)-3-(4-hydroxyphenyl)prop-2-enoic acid | (2E)-3...)copy SMILEScopy InChI
Affinity DataKi:  5.37E+5nM ΔG°:  -18.7kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion using s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4N46PubMed