Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Carbonic anhydrase 2' and Ligand = 'BDBM7461'
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£ degli Studi di Cagliari

Curated by ChEMBL
LigandPNGBDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)copy SMILEScopy InChI
Affinity DataKi:  4.31E+3nMAssay Description:Inhibition of cytosolic human carbonic anhydrase 2 preincubated for 12 hrs by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J1045TPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£ degli Studi di Cagliari

Curated by ChEMBL
LigandPNGBDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)copy SMILEScopy InChI
Affinity DataKi:  4.38E+3nMAssay Description:Inhibition of cytosolic human carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J1045TPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£ degli Studi di Cagliari

Curated by ChEMBL
LigandPNGBDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nM ΔG°: >-28.5kJ/moleT: 2°CAssay Description:Inhibition of human recombinant carbonic anhydrase 2 preincubated for 15 mins at room temperature/6 hrs at 4 deg C by stopped-flow CO2 hydration assa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862J84PubMed