Compile Data Set for Download or QSAR
Found 5 Enz. Inhib. hit(s) with Target = 'Carbonic anhydrase 3' and Ligand = 'BDBM10888'
TargetCarbonic anhydrase 3(Bos taurus (Cattle))
Ondokuz Mayis University

LigandPNGBDBM10888(1,2-benzoxazol-3-ylmethanesulfonamide | CHEMBL750 ...)copy SMILEScopy InChI
Affinity DataKi:  8.50E+3nMpH: 7.4Assay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR4W1FPubMed
TargetCarbonic anhydrase 3(Bos taurus (Cattle))
Ondokuz Mayis University

LigandPNGBDBM10888(1,2-benzoxazol-3-ylmethanesulfonamide | CHEMBL750 ...)copy SMILEScopy InChI
Affinity DataKi:  8.51E+3nMAssay Description:Inhibition of bovine carbonic anhydrase 3 using 4-nitrophenylacetate as substrate after 3 mins using spectrophotometry by Lineweaver-Burk plot analys...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N0170SPubMed
TargetCarbonic anhydrase 3(Homo sapiens (Human))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM10888(1,2-benzoxazol-3-ylmethanesulfonamide | CHEMBL750 ...)copy SMILEScopy InChI
Affinity DataKi:  2.20E+6nMAssay Description:Inhibition of human recombinant CA3 by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6M96PubMedDrugBank
TargetCarbonic anhydrase 3(Homo sapiens (Human))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM10888(1,2-benzoxazol-3-ylmethanesulfonamide | CHEMBL750 ...)copy SMILEScopy InChI
Affinity DataKi:  2.20E+6nMAssay Description:Inhibition of human recombinant CA 3 assessed as CO2 hydration by stopped flow kinetic assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8NJ9PubMedDrugBank
TargetCarbonic anhydrase 3(Homo sapiens (Human))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM10888(1,2-benzoxazol-3-ylmethanesulfonamide | CHEMBL750 ...)copy SMILEScopy InChI
Affinity DataKi:  2.20E+6nM ΔG°:  -14.9kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2833QHPPubMedDrugBank