Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Carboxylic ester hydrolase' and Ligand = 'BDBM8962'
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Universita di Siena

LigandPNGBDBM8962(Bis-THA inhibitor 4 | CHEMBL179732 | N-[5-(1,2,3,4...)copy SMILEScopy InChI
Affinity DataKi:  100nMAssay Description:Inhibition of enzyme activity was measured over a substrate concentration range of 0.01-30 mM and at least six inhibitor concentrations to determine ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8WMJPubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Institute of Science

Curated by ChEMBL
LigandPNGBDBM8962(Bis-THA inhibitor 4 | CHEMBL179732 | N-[5-(1,2,3,4...)copy SMILEScopy InChI
Affinity DataIC50: 329nMAssay Description:Inhibition of rat serum BuChEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154GPXPubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Institute of Science

Curated by ChEMBL
LigandPNGBDBM8962(Bis-THA inhibitor 4 | CHEMBL179732 | N-[5-(1,2,3,4...)copy SMILEScopy InChI
Affinity DataIC50: 329nMAssay Description:Inhibition of rat BuChEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z16D4PubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Institute of Science

Curated by ChEMBL
LigandPNGBDBM8962(Bis-THA inhibitor 4 | CHEMBL179732 | N-[5-(1,2,3,4...)copy SMILEScopy InChI
Affinity DataIC50: 329nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43R9QPubMed