Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Caspase-3' and Ligand = 'BDBM10335'
TargetCaspase-3(Homo sapiens (Human))
Chugai Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM10335((S)-1-(6-Fluoropyridin-3-yl-methyl)-5-(2-phenoxyme...)copy SMILEScopy InChI
Affinity DataIC50: 10.2nMAssay Description:Inhibition of caspase3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VTJPubMed
TargetCaspase-3(Homo sapiens (Human))
Chugai Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM10335((S)-1-(6-Fluoropyridin-3-yl-methyl)-5-(2-phenoxyme...)copy SMILEScopy InChI
Affinity DataIC50: 10.3nMpH: 7.4 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40SDNPubMed