Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Cathepsin B' and Ligand = 'BDBM16510'
TargetCathepsin B(Homo sapiens (Human))
National Chemical Laboratory (CSIR-NCL)

Curated by ChEMBL
LigandPNGBDBM16510((2S,3S)-3-[[(1S)-1-(isoamylcarbamoyl)-3-methyl-but...)copy SMILEScopy InChI
Affinity DataKi:  3.36nMAssay Description:Inhibition of cathepsin BMore data for this Ligand-Target Pair
TargetCathepsin B(Homo sapiens (Human))
National Chemical Laboratory (CSIR-NCL)

Curated by ChEMBL
LigandPNGBDBM16510((2S,3S)-3-[[(1S)-1-(isoamylcarbamoyl)-3-methyl-but...)copy SMILEScopy InChI
Affinity DataIC50: 1.53nMpH: 6.8 T: 2°CAssay Description:Screening Center: Penn Center for Molecular Discovery Center Affiliation: University of Pennsylvania Network: Molecular Library Screening Center Netw...More data for this Ligand-Target Pair
TargetCathepsin B(Bos taurus (bovine))
Osaka University of Pharmaceutical Sciences

LigandPNGBDBM16510((2S,3S)-3-[[(1S)-1-(isoamylcarbamoyl)-3-methyl-but...)copy SMILEScopy InChI
Affinity DataIC50: 40nMpH: 6.0 T: 2°CAssay Description:Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor...More data for this Ligand-Target Pair