Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Cathepsin K' and Ligand = 'BDBM19775'
TargetCathepsin K(Homo sapiens (Human))
GSK

LigandPNGBDBM19775((2S)-2-(1-benzofuran-2-ylformamido)-4-methyl-N-[(4...)copy SMILEScopy InChI
Affinity DataKi:  0.140nM ΔG°:  -55.7kJ/molepH: 5.5 T: 2°CAssay Description:Potential inhibitors were evaluated using the progress curve method. Assays were carried out in the presence of variable concentrations of test compo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8XP5PubMed
TargetCathepsin K(Rattus norvegicus)
GSK

LigandPNGBDBM19775((2S)-2-(1-benzofuran-2-ylformamido)-4-methyl-N-[(4...)copy SMILEScopy InChI
Affinity DataKi:  73nMAssay Description:Potential inhibitors were evaluated using the progress curve method. Assays were carried out in the presence of variable concentrations of test compo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8XP5PubMed