TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
Affinity DataKi: 140nMAssay Description:Inhibitory constant of the compound against human cathepsin KMore data for this Ligand-Target Pair
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibitory activity tested against Human Cathepsin K receptor using gelatinase assayMore data for this Ligand-Target Pair
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibitory constant of the compound against human cathepsin KMore data for this Ligand-Target Pair
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibitory activity tested against Human Cathepsin K using Z-Phe-Arg-pNA as substrateMore data for this Ligand-Target Pair
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 50nMpH: 7.0Assay Description:Inhibition of Cathepsin K at pH 7More data for this Ligand-Target Pair
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 60nMpH: 5.5Assay Description:Inhibition of Cathepsin K at pH 5.5More data for this Ligand-Target Pair
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 90nMpH: 5.5Assay Description:Effect of 10 mM of GSH on the inhibitory activity of compound against Cathepsin K, at pH 5.5More data for this Ligand-Target Pair
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 150nMpH: 7.0Assay Description:Effect of 10 mM of GSH on the inhibitory activity against Cathepsin K, at pH 7More data for this Ligand-Target Pair
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 1.41E+3nMAssay Description:Inhibitory activity tested against Human Cathepsin K receptor using bone resorption assayMore data for this Ligand-Target Pair