Found 47 Enz. Inhib. hit(s) with Target = 'Cholinesterase' and Ligand = 'BDBM11682' 
Affinity DataIC50: 14nMAssay Description:Inhibition of human serum BuChE using butyrylthiocholine iodide as substrate preincubated with enzyme for 10 mins followed by substrate addition and ...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of BChE (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inhibition of human BuChE using S-butyrylthiocholine as substrate preincubated for 30 mins followed by substrate addition and measured after 25 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 58nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated with enzyme for 20 mins followed by substrate addition and...More data for this Ligand-Target Pair
TargetCholinesterase(Mus musculus (Mouse))
Chinese Academy of Medical Sciences and Peking Union Medical College
Curated by ChEMBL
Chinese Academy of Medical Sciences and Peking Union Medical College
Curated by ChEMBL
Affinity DataIC50: 58nMAssay Description:Inhibition of mouse plasma BuChE using S-butyrylacetylthiocholine iodide as substrate measured after 30 mins by Ellman's method relative to controlMore data for this Ligand-Target Pair
Affinity DataIC50: 260nMAssay Description:Inhibition of butyrylcholinesterase (unknown origin) using butyrylthiocholine iodide as substrate after 25 mins by Ellmann methodMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine as substrate by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of recombinant human BuChe using S-butyrylthiocholine iodide as substrate measured after 7 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 301nMAssay Description:Inhibition of human serum BuChE using acetylthiocholine iodide as substrate preincubated for 20 to 60 mins followed by substrate addition by Ellman's...More data for this Ligand-Target Pair
Affinity DataIC50: 301nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 to 60 mins followed by substrate addition by Ellman's...More data for this Ligand-Target Pair
Affinity DataIC50: 370nMAssay Description:Inhibition of human BuChE using butyrylthiocholine as substrate after 1 min by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 380nMAssay Description:Inhibition of human serum BChE using S-Butyrylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition by Ellman's met...More data for this Ligand-Target Pair
Affinity DataIC50: 495nMAssay Description:Inhibition of equine BuChE using ACTI as substrate preincubated for 29 mins followed by substrate addition measured at 1 min intervals for 10 mins by...More data for this Ligand-Target Pair
Affinity DataIC50: 560nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated with enzyme for 20 mins followed by addition of substrate ...More data for this Ligand-Target Pair
Affinity DataIC50: 560nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated with enzyme for 20 mins followed by substrate addition by ...More data for this Ligand-Target Pair
Affinity DataIC50: 678nMAssay Description:Inhibition concentration against human adenosine kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 785nMAssay Description:Inhibition of equine serum BChE using S-butyrylthiocholine iodide as substrate preincubated for 60 mins followed by substrate addition and measured f...More data for this Ligand-Target Pair
Affinity DataIC50: 803nMAssay Description:Inhibition of human BuChE using ACTI as substrate incubated for 40 mins measured at 1 min intervals for 10 mins by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of horse serum BuChE using butyrylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition by Ellman's meth...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human serum butyrylcholinesterase using BTCI as substrate pre-incubated for 10 mins followed by substrate addition and measured for 6 m...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of equine serum BuChE using BTC as substrate after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.22E+3nMAssay Description:Inhibition of human BChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.22E+3nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by Ellman's metho...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of equine serum BuChE using S-butyrylthiocholine iodide as susbtrate preincubated for 6 mins followed by substrate addition measured up to...More data for this Ligand-Target Pair
Affinity DataIC50: 1.32E+3nMAssay Description:Inhibition of equine serum BuChE preincubated for 5 mins followed by addition of butyrylthiocholine iodide as substrate measured after 2 mins by Ellm...More data for this Ligand-Target Pair
Affinity DataIC50: 1.44E+3nMAssay Description:Inhibition of human BuchE using butyrylthiocholine iodide as substrate preincubated for 30 mins followed by substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.51E+3nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine chloride as substrate preincubated for 15 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine as substrate incubated for 5 mins followed by substrate addition and measured after 5 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.71E+3nMAssay Description:Inhibition of human serum BuChE using butyrylthiocholine iodide as substrate preincubated with enzyme for 5 mins followed by substrate addition and m...More data for this Ligand-Target Pair
Affinity DataIC50: 2.86E+3nMAssay Description:Inhibition of BuChE (unknown origin) preincubated for 30 mins followed by substrate addition acetylthiocholineiodide measured after 40 mins by Ellman...More data for this Ligand-Target Pair
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of human serum BChE using acetylthiocholine iodide as substrate measured after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of human serum BuChE using acetylcholine iodide as substrate incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of horse serum butyrylcholinesterase using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition m...More data for this Ligand-Target Pair
Affinity DataIC50: 6.27E+3nMAssay Description:Inhibition of dog serum BChE using butrylthiocholine iodide as substrate by spectrophotometry based Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 7.72E+3nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition measured after ...More data for this Ligand-Target Pair
Affinity DataIC50: 7.72E+3nMAssay Description:Inhibition of equine serum BuChE preincubated for 15 mins followed by substrate addition and measured after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 9.12E+3nMAssay Description:Inhibition of human CholinesteraseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human BuChE using S-butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured for 60 to 30...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+4nMAssay Description:The potential of the compounds of the present invention to inhibit acetylcholinesterase and butyrylcholinesterase enzymes were tested according to th...More data for this Ligand-Target Pair
Affinity DataKd: 1.15E+3nMAssay Description:Pseudo-irreversible inhibition of equine serum BuChE assessed as binding affinity in an equilibrium state using butyrylthiocholine iodide as substrat...More data for this Ligand-Target Pair
