Compile Data Set for Download or QSAR
Found 38 Enz. Inhib. hit(s) with Target = 'Cholinesterase' and Ligand = 'BDBM50004000'
TargetCholinesterase(Equus caballus (Horse))
TBA

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)copy SMILEScopy InChI
Affinity DataKi:  41nMAssay Description:Time dependent inhibition of equine serum BChE assessed as stability constants of inhibitor-enzyme complex using acetylthiocholine as substrate after...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P27079PubMed
TargetCholinesterase(Homo sapiens (Human))
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)copy SMILEScopy InChI
Affinity DataKi:  5.00E+3nMAssay Description:Inhibition of anticholinesterase activity by their ability to inactivate human serum butyrylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ3374PubMed
TargetCholinesterase(Equus caballus (Horse))
TBA

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of BChE in horse serum using butyrylthiocholine iodide as substrate after 120 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P6220PubMed
TargetCholinesterase(Homo sapiens (Human))
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibitory activity against Butyrylcholinesterase in plasmaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24M93HFPubMed
TargetCholinesterase(Homo sapiens (Human))
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibitory activity against Acetylcholinesterase in electric eelMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24M93HFPubMed
TargetCholinesterase(Homo sapiens (Human))
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of human plasma BChE pretreated for 30 mins by Ellman techniqueMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6SHBPubMed
TargetCholinesterase(Homo sapiens (Human))
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of BuChE (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7S9XPubMed
TargetCholinesterase(Homo sapiens (Human))
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of human ButyrylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8BW2PubMed
TargetCholinesterase(Homo sapiens (Human))
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)copy SMILEScopy InChI
Affinity DataIC50: 16nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2MW1PubMed
TargetCholinesterase(Homo sapiens (Human))
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibitory concentration against human plasma ButyrylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7BWQPubMed
TargetCholinesterase(Homo sapiens (Human))
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M37S1PubMed
TargetCholinesterase(Homo sapiens (Human))
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibitory activity against butyrylcholinesterase (BChE) in human erythrocyteMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NG4RX2PubMed
TargetCholinesterase(Homo sapiens (Human))
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of human plasma BuchE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0NJ3PubMed
TargetCholinesterase(Homo sapiens (Human))
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:In vitro inhibition of human butryl cholinesterase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q200012XPubMed
TargetCholinesterase(Homo sapiens (Human))
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:The compound was evaluated for the inhibition human of ButyrylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28K79QRPubMed
TargetCholinesterase(Equus caballus (Horse))
TBA

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of equine serum BChE using ATC iodide substrate by DTNB based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98C3DPubMed
TargetCholinesterase(Equus caballus (Horse))
TBA

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Inhibition of equine serum BChE using acetylthiocholine as substrate after 2 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P27079PubMed
TargetCholinesterase(Equus caballus (Horse))
TBA

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of equine serum BChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B32VGPubMed
TargetCholinesterase(Homo sapiens (Human))
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)copy SMILEScopy InChI
Affinity DataIC50: 73nMAssay Description:In vitro inhibition of Butyrylcholinesterase from human serumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52NN0PubMed
TargetCholinesterase(Homo sapiens (Human))
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)copy SMILEScopy InChI
Affinity DataIC50: 73nMAssay Description:Concentration required to inhibit 50% of Butyrylcholinesterase obtained from human serum was determined in vitroMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21N81S7PubMed
TargetCholinesterase(Equus caballus (Horse))
TBA

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)copy SMILEScopy InChI
Affinity DataIC50: 78nMAssay Description:Inhibition of equine serum butyrylcholinesterase using butyrylcholine iodide as substrate preincubated for 30 mins followed by substrate addition mea...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7J4DPubMed
TargetCholinesterase(Homo sapiens (Human))
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)copy SMILEScopy InChI
Affinity DataIC50: 129nMAssay Description:Inhibitory activity against Butyrylcholinesterase in cortexMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24M93HFPubMed
TargetCholinesterase(Homo sapiens (Human))
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)copy SMILEScopy InChI
Affinity DataIC50: 129nMAssay Description:Inhibitory activity against Acetylcholinesterase in erythrocyteMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24M93HFPubMed
TargetCholinesterase(Homo sapiens (Human))
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of human BuChE using butyrylthiocholine iodide as substrate measured for 1 min by spectrophotometric based Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9VQ0PubMed
TargetCholinesterase(Equus caballus (Horse))
TBA

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Inhibition of equine serum BChE using S-butyrylthiocholine chloride as substrate incubated for 30 mins by Ellman's microplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47R34PubMed
TargetCholinesterase(Mus musculus (Mouse))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Inhibition of mouse serum BChE after 1 hr by modified Ellman's colorimetric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0NV4PubMed
TargetCholinesterase(Mus musculus (Mouse))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Inhibition of mouse serum BChE after 1 hr by modified Ellman's colorimetric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27S7NWWPubMed
TargetCholinesterase(Homo sapiens (Human))
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of human BuChE using butyrylthiocholine chloride as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7N4ZPubMed
TargetCholinesterase(Equus caballus (Horse))
TBA

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)copy SMILEScopy InChI
Affinity DataIC50: 580nMAssay Description:Inhibition of equine serum BChE preincubated for 15 mins followed by addition of S-butyrylthiocholine chloride as substrate measured after 30 mins by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7RFMPubMed
TargetCholinesterase(Equus caballus (Horse))
TBA

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)copy SMILEScopy InChI
Affinity DataIC50: 850nMAssay Description:Inhibition of equine serum BCHE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition measured after 3...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9FDXPubMed
TargetCholinesterase(Homo sapiens (Human))
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)copy SMILEScopy InChI
Affinity DataIC50: 850nMAssay Description:Inhibition of BChE (unknown origin) using butyrylthiocholine chloride as substrate preincubated for 30 mins before substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4SQSPubMed
TargetCholinesterase(Homo sapiens (Human))
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)copy SMILEScopy InChI
Affinity DataIC50: 850nMAssay Description:Inhibition of BChE (unknown origin) using butyryl thiocholine iodide as substrate after 30 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q216K
TargetCholinesterase(Homo sapiens (Human))
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)copy SMILEScopy InChI
Affinity DataIC50: 850nMAssay Description:Inhibition of BuChE (unknown origin) using butyrylthiocholine chloride as substrate preincubated for 15 mins followed by substrate addition measured ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B92D9PubMed
TargetCholinesterase(Equus caballus (Horse))
TBA

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)copy SMILEScopy InChI
Affinity DataIC50: 857nMAssay Description:Inhibition of horse BChEMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20R9P54PubMed
TargetCholinesterase(Homo sapiens (Human))
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)copy SMILEScopy InChI
Affinity DataIC50: 857nMAssay Description:Inhibition of BChE (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862G6DPubMed
TargetCholinesterase(Homo sapiens (Human))
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)copy SMILEScopy InChI
Affinity DataIC50: 930nMAssay Description:Inhibition of BChE (unknown origin) using BCh iodide as substrate preincubated for 15 mins prior to substrate addition measured after 10 mins by Ellm...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2C6SPubMed
TargetCholinesterase(Homo sapiens (Human))
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of BChEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DBZPubMed
TargetCholinesterase(Equus caballus (Horse))
TBA

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)copy SMILEScopy InChI
Affinity DataIC50: 1.34E+3nMAssay Description:Inhibition of equine serum BChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78G5XPubMed