Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Coagulation factor X' and Ligand = 'BDBM13616'
TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharma Deutschland GmbH

LigandPNGBDBM13616(3-Oxybenzamide 2 | 3-[2-(2,4-dichlorophenyl)ethoxy...)copy SMILEScopy InChI
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9THZPubMed
TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharma Deutschland GmbH

LigandPNGBDBM13616(3-Oxybenzamide 2 | 3-[2-(2,4-dichlorophenyl)ethoxy...)copy SMILEScopy InChI
Affinity DataKi:  50nMAssay Description:Binding affinity to human factor 10a using S-2765 as substrate preincubated for 15 mins followed by substrate addition measured between 1 and 5 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28918HMPubMed
TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharma Deutschland GmbH

LigandPNGBDBM13616(3-Oxybenzamide 2 | 3-[2-(2,4-dichlorophenyl)ethoxy...)copy SMILEScopy InChI
Affinity DataKi:  50nMAssay Description:Inhibitory activity against human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5WW7PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharma Deutschland GmbH

LigandPNGBDBM13616(3-Oxybenzamide 2 | 3-[2-(2,4-dichlorophenyl)ethoxy...)copy SMILEScopy InChI
Affinity DataKi:  50.1nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6TGMPubMed