Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Coagulation factor XI' and Ligand = 'BDBM349979'
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM349979((E)-4-(2-(3-(5-Chloro-2-(1H-tetrazol-1-yl)phenyl)a...)copy SMILEScopy InChI
Affinity DataKi:  5.80nMAssay Description:Inhibition of human factor 11a using pyro-Glu-Pro-Arg-pNA as substrate at 37 degC after 10 to 120 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K64MHNPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM349979((E)-4-(2-(3-(5-Chloro-2-(1H-tetrazol-1-yl)phenyl)a...)copy SMILEScopy InChI
Affinity DataKi:  7.5nMAssay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N018P5US Patent