Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Collagenase 3' and Ligand = 'BDBM26550'
TargetCollagenase 3(Homo sapiens (Human))
Vertex Pharmaceuticals

LigandPNGBDBM26550(2-{[4-(but-2-yn-1-yloxy)benzene](methyl)sulfonamid...)copy SMILEScopy InChI
Affinity DataKi:  17nM ΔG°:  -43.9kJ/molepH: 7.4 T: 2°CAssay Description:A continuous assay was used in which the substrate is a synthetic peptide containing a fluorescent group (7-methoxycoumarin), which is quenched by en...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1H67PubMed
TargetCollagenase 3(Homo sapiens (Human))
Vertex Pharmaceuticals

LigandPNGBDBM26550(2-{[4-(but-2-yn-1-yloxy)benzene](methyl)sulfonamid...)copy SMILEScopy InChI
Affinity DataKi:  17nM ΔG°:  -43.9kJ/molepH: 7.4 T: 2°CAssay Description:A continuous assay was used in which the substrate is a synthetic peptide containing a fluorescent group (7-methoxycoumarin), which is quenched by en...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930RH8PubMed
TargetCollagenase 3(Homo sapiens (Human))
Vertex Pharmaceuticals

LigandPNGBDBM26550(2-{[4-(but-2-yn-1-yloxy)benzene](methyl)sulfonamid...)copy SMILEScopy InChI
Affinity DataIC50: 99nMAssay Description:In vitro inhibition of Matrix metalloprotein 13More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21N80H7PubMed