Compile Data Set for Download or QSAR
Found 10 Enz. Inhib. hit(s) with Target = 'Collagenase 3' and Ligand = 'BDBM50063917'
TargetCollagenase 3(Homo sapiens (Human))TBA
LigandPNGBDBM50063917((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...)copy SMILEScopy InChI
Affinity DataIC50: 0.740nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB281XPubMedDrugBank
TargetCollagenase 3(Homo sapiens (Human))TBA
LigandPNGBDBM50063917((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibition of Matrix metalloprotease-13 (MMP-13) in fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP747BPubMedDrugBank
TargetCollagenase 3(Homo sapiens (Human))TBA
LigandPNGBDBM50063917((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMMore data for this Ligand-Target Pair
In DepthDetails DrugBank
TargetCollagenase 3(Homo sapiens (Human))TBA
LigandPNGBDBM50063917((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of Coll-3 MMP-13More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25H7FGNPubMedDrugBank
TargetCollagenase 3(Homo sapiens (Human))TBA
LigandPNGBDBM50063917((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:50 percent inhibition of human Matrix metalloprotease-13 by the cleavage of fluorogenic peptide MCA-Pro-Leu-Gly-Leu-Dpa-ala-Arg-NH2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZK5H6ZPubMedDrugBank
TargetCollagenase 3(Homo sapiens (Human))TBA
LigandPNGBDBM50063917((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against human Matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29G5NCXPubMedDrugBank
TargetCollagenase 3(Homo sapiens (Human))TBA
LigandPNGBDBM50063917((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...)copy SMILEScopy InChI
Affinity DataIC50: 3.40nMAssay Description:Inhibition of Matrix metalloproteinase-13More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3KD9PubMedDrugBank
TargetCollagenase 3(Homo sapiens (Human))TBA
LigandPNGBDBM50063917((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...)copy SMILEScopy InChI
Affinity DataIC50: 3.40nMAssay Description:Inhibitory activity against matrix metalloprotease-13 (MMP13)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC11FFPubMedDrugBank
TargetCollagenase 3(Homo sapiens (Human))TBA
LigandPNGBDBM50063917((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20002K2PubMedDrugBank
TargetCollagenase 3(Homo sapiens (Human))TBA
LigandPNGBDBM50063917((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...)copy SMILEScopy InChI
Affinity DataIC50: 128nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057KZKPubMedDrugBank