Compile Data Set for Download or QSAR
Found 6 Enz. Inhib. hit(s) with Target = 'Complement factor B' and Ligand = 'BDBM155872'
TargetComplement factor B(Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM155872(US10093663, Example 2b | US9682968, Example-1)copy SMILES
Affinity DataIC50: 100nMAssay Description:CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XG9P9JUS Patent
TargetComplement factor B(Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM155872(US10093663, Example 2b | US9682968, Example-1)copy SMILES
Affinity DataIC50: 7.90E+3nMpH: 7.4 T: 2°CAssay Description:CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DF6T75US Patent
TargetComplement factor B(Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM155872(US10093663, Example 2b | US9682968, Example-1)copy SMILES
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of human serine protease factor B catalytic domain (D470 to L764 residues) assessed as inhibition of cleavage cobra venom factor (CVF):Bb ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N84P4PubMed
TargetComplement factor B(Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM155872(US10093663, Example 2b | US9682968, Example-1)copy SMILES
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human serine protease factor B by TR-FRET based competition binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N84P4PubMed
TargetComplement factor B(Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM155872(US10093663, Example 2b | US9682968, Example-1)copy SMILES
Affinity DataIC50: 1.00E+5nMpH: 7.4 T: 2°CAssay Description:CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DF6T75US Patent
TargetComplement factor B(Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM155872(US10093663, Example 2b | US9682968, Example-1)copy SMILES
Affinity DataIC50: 1.00E+5nMpH: 7.4 T: 2°CAssay Description:CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DF6T75US Patent