Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Complement factor D' and Ligand = 'BDBM474862'
TargetComplement factor D(Homo sapiens (Human))TBA
LigandPNGBDBM474862(US10849883, Compound 279a | US11559515, Compound 2...)copy SMILEScopy InChI
Affinity DataKi:  19nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X5CW8PubMed
TargetComplement factor D(Homo sapiens (Human))TBA
LigandPNGBDBM474862(US10849883, Compound 279a | US11559515, Compound 2...)copy SMILEScopy InChI
Affinity DataIC50: 37nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X5CW8PubMed
TargetComplement factor D(Homo sapiens (Human))TBA
LigandPNGBDBM474862(US10849883, Compound 279a | US11559515, Compound 2...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:An established esterolytic assay for the measurement of Factor D activity and inhibition of Factor D activity was used (Kam, C. M.; McRae, B. J.; Har...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J6FZZUS Patent
TargetComplement factor D(Homo sapiens (Human))TBA
LigandPNGBDBM474862(US10849883, Compound 279a | US11559515, Compound 2...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:An established esterolytic assay for the measurement of Factor D activity and inhibition of Factor D activity was used (Kam, C. M.; McRae, B. J.; Har...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DN48Z8US Patent