Found 4 Enz. Inhib. hit(s) with Target = 'Complement factor D' and Ligand = 'BDBM50524338' TargetComplement factor D(Homo sapiens (Human))
Novartis Institutes for BioMedical Research
Curated by ChEMBL
Novartis Institutes for BioMedical Research
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of 2-((1E,3E,5E)-5-(1-(6-((((3S,5S)-1-((1-carbamoyl-1H-indol-3-yl)carbamoyl)-5-((3-chloro-2-fluorobenzyl)carbamoyl)-3-fluoropyrrolidin-3-y...More data for this Ligand-Target Pair
TargetComplement factor D(Homo sapiens (Human))
Novartis Institutes for BioMedical Research
Curated by ChEMBL
Novartis Institutes for BioMedical Research
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant human CFD expressed in Escherichia coli incubated up to 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
TargetComplement factor D(Homo sapiens (Human))
Novartis Institutes for BioMedical Research
Curated by ChEMBL
Novartis Institutes for BioMedical Research
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of human complement FD by TR-FRET assayMore data for this Ligand-Target Pair
TargetComplement factor D(Homo sapiens (Human))
Novartis Institutes for BioMedical Research
Curated by ChEMBL
Novartis Institutes for BioMedical Research
Curated by ChEMBL
Affinity DataIC50: 270nMAssay Description:Inhibition of FD-mediated alternative complementation pathway in 50% human whole blood assessed as reduction in zymosan-induced membrane-attack compl...More data for this Ligand-Target Pair
