Found 4 Enz. Inhib. hit(s) with Target = 'Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'' and Ligand = 'BDBM14390' TargetCone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'(Homo sapiens (Human))
CSIR-Indian Institute of Integrative Medicine
Curated by ChEMBL
CSIR-Indian Institute of Integrative Medicine
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of human PDE5A1 expressed in baculovirus in sf9 cells by PDE Glo phosphodiesterase assayMore data for this Ligand-Target Pair
TargetCone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'(Homo sapiens (Human))
CSIR-Indian Institute of Integrative Medicine
Curated by ChEMBL
CSIR-Indian Institute of Integrative Medicine
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibition of N-terminal GST-tagged human PDE6C expressed in baculovirus infected sf9 cells using [3H]cGMP as substrate measured after 30 mins by sci...More data for this Ligand-Target Pair
TargetCone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'(Homo sapiens (Human))
CSIR-Indian Institute of Integrative Medicine
Curated by ChEMBL
CSIR-Indian Institute of Integrative Medicine
Curated by ChEMBL
Affinity DataIC50: 39nMAssay Description:Inhibition of human recombinant PDE6C at 1 uM by [3H]cGMP based tritium scintillation proximity assayMore data for this Ligand-Target Pair
TargetCone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'(Homo sapiens (Human))
CSIR-Indian Institute of Integrative Medicine
Curated by ChEMBL
CSIR-Indian Institute of Integrative Medicine
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibition of human PDE6CMore data for this Ligand-Target Pair
