Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Cyclin-H/Cyclin-dependent kinase 7' and Ligand = 'BDBM27217'
TargetCyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
Universit£ degli Studi di Palermo

Curated by ChEMBL
LigandPNGBDBM27217((2R)-2-{[4-(benzylamino)-8-(propan-2-yl)pyrazolo[1...)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Inhibition of human recombinant CDK7/cyclin H using histone H1 and [gamma-33P]ATP incubated fro 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6NRFPubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
Universit£ degli Studi di Palermo

Curated by ChEMBL
LigandPNGBDBM27217((2R)-2-{[4-(benzylamino)-8-(propan-2-yl)pyrazolo[1...)copy SMILEScopy InChI
Affinity DataIC50: 500nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 15 uM ATP/ [gamma-33P]...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ024JPubMed