Compile Data Set for Download or QSAR
Found 5 Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase 1' and Ligand = 'BDBM50110183'
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
SHANGHAI PHARMACEUTICALS HOLDING CO., LTD.

US Patent
LigandPNGBDBM50110183(Abemaciclib | LY-2835219 | US10626107, Example LY2...)copy SMILEScopy InChI
Affinity DataIC50: 263nMAssay Description:1. Take 10 mM stock solution of the test compound, in 96-well compound plate, DMSO was used to dilute the compound to an initial concentration of 100...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GX4FKSUS Patent
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
SHANGHAI PHARMACEUTICALS HOLDING CO., LTD.

US Patent
LigandPNGBDBM50110183(Abemaciclib | LY-2835219 | US10626107, Example LY2...)copy SMILEScopy InChI
Affinity DataIC50: 263nMAssay Description:1. Take 10 mM stock solution of the test compound, in 96-well compound plate, DMSO was used to dilute the compound to an initial concentration of 100...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR8047US Patent
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
SHANGHAI PHARMACEUTICALS HOLDING CO., LTD.

US Patent
LigandPNGBDBM50110183(Abemaciclib | LY-2835219 | US10626107, Example LY2...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of CDK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53QDZPubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
SHANGHAI PHARMACEUTICALS HOLDING CO., LTD.

US Patent
LigandPNGBDBM50110183(Abemaciclib | LY-2835219 | US10626107, Example LY2...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of CDK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0C84PubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
SHANGHAI PHARMACEUTICALS HOLDING CO., LTD.

US Patent
LigandPNGBDBM50110183(Abemaciclib | LY-2835219 | US10626107, Example LY2...)copy SMILEScopy InChI
Affinity DataIC50: 1.52E+3nMAssay Description:Inhibition of CDK1 (unknown origin) using U-light as substrate preincubated for 1 hr followed by EDTA addition measured after 1 hr by LANCE Ultra kin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H134K1PubMed