Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase 4/G1/S-specific cyclin-D1 [L188C]' and Ligand = 'BDBM6253'
LigandPNGBDBM6253(8-Cyclopentyl-2-phenylamino-8H-pyrido[2,3-d]pyrimi...)copy SMILEScopy InChI
Affinity DataIC50: 210nMpH: 7.4 T: 2°CAssay Description:The enzyme was assayed with substrate GST- retinoblastoma in the presence of 25 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which in...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J97Z9PubMed
LigandPNGBDBM6253(8-Cyclopentyl-2-phenylamino-8H-pyrido[2,3-d]pyrimi...)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:The enzyme was assayed with substrate GST- retinoblastoma in the presence of 25 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which in...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25B00N4PubMed