Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
Found
1
Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase 4' and Ligand = 'BDBM112496'
Target
Cyclin-dependent kinase 4
(Homo sapiens (Human))
Amgen Inc.
US Patent
Ligand
BDBM112496
(US8623885, 37)
copy SMILES
copy InChI
Affinity Data
IC50: 3nM
pH: 7.4
Assay Description:
The CDK4 and CDK1 inhibitory activity of the CDK4/6-FLT3 inhibitors was determined with a filtration kinase assay. The compounds, kinase and substrat...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q2DZ06Z1
US Patent