Compile Data Set for Download or QSAR
Found 6 Enz. Inhib. hit(s) with Target = 'Cysteinyl leukotriene receptor 1/2' and Ligand = 'BDBM50006812'
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50006812(7-[3-(4-Acetyl-3-hydroxy-2-propyl-phenoxy)-2-hydro...)copy SMILEScopy InChI
Affinity DataKi:  1.00E+3nMAssay Description:In vitro binding affinity against cysteinyl leukotriene D4 receptor from guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29C6WDMPubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50006812(7-[3-(4-Acetyl-3-hydroxy-2-propyl-phenoxy)-2-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:In vitro inhibition of SRS-A-induced contractions in guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D220TJPubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50006812(7-[3-(4-Acetyl-3-hydroxy-2-propyl-phenoxy)-2-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of LTD4-induced contraction in guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25X2B45PubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50006812(7-[3-(4-Acetyl-3-hydroxy-2-propyl-phenoxy)-2-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 510nMAssay Description:Inhibition of the spasmogenic activity of LTD4 in guinea pig parenchymal strips.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TB15WMPubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50006812(7-[3-(4-Acetyl-3-hydroxy-2-propyl-phenoxy)-2-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibitory activity to block binding of [3H]leukotriene D4 to LTD4 receptor sites in homogenized guinea pig lungMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3C8BPubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50006812(7-[3-(4-Acetyl-3-hydroxy-2-propyl-phenoxy)-2-hydro...)copy SMILEScopy InChI
Affinity DataKd:  1.12E+3nMAssay Description:Displacement of [3H]LTD4 from Cysteinyl leukotriene D4 receptor in guinea pig lung membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25141XJPubMed