Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Cytochrome P450 11B2, mitochondrial' and Ligand = 'BDBM50378956'
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
UNIVERSITAET DES SAARLANDES CAMPUS SAARBRUECKEN

US Patent
LigandPNGBDBM50378956(CHEMBL2011246 | US9394290, 11)copy SMILEScopy InChI
Affinity DataIC50: 237nMT: 2°CAssay Description:V79MZ cells expressing human CYP11B1 and human CYP11B2 genes, respectively, were grown on 24-well cell culture plates (8×10^5 cells per well) w...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24T6H86US Patent
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
UNIVERSITAET DES SAARLANDES CAMPUS SAARBRUECKEN

US Patent
LigandPNGBDBM50378956(CHEMBL2011246 | US9394290, 11)copy SMILEScopy InChI
Affinity DataIC50: 237nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6RJ2PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
UNIVERSITAET DES SAARLANDES CAMPUS SAARBRUECKEN

US Patent
LigandPNGBDBM50378956(CHEMBL2011246 | US9394290, 11)copy SMILEScopy InChI
Affinity DataIC50: 237nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZ cells using [1,2-3H]11-deoxycorticosterone as substrate preincubated for 60 mins prior to subs...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3T0WPubMed