Compile Data Set for Download or QSAR
Found 6 Enz. Inhib. hit(s) with Target = 'Cytochrome P450 1B1' and Ligand = 'BDBM23926'
TargetCytochrome P450 1B1(Homo sapiens (Human))
University of Tokyo

LigandPNGBDBM23926((E)-resveratrol | 5-[(E)-2-(4-hydroxyphenyl)etheny...)copy SMILEScopy InChI
Affinity DataKi:  177nM ΔG°:  -40.1kJ/molepH: 8.0 T: 2°CAssay Description:The ethoxyresorufin-O-deethylase (EROD) assay is used to test the activity of CYP1B1. More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46QDGPubMed
TargetCytochrome P450 1B1(Homo sapiens (Human))
University of Tokyo

LigandPNGBDBM23926((E)-resveratrol | 5-[(E)-2-(4-hydroxyphenyl)etheny...)copy SMILEScopy InChI
Affinity DataKi:  750nMAssay Description:Mixed type inhibition of human CYP1B1 by EROD assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930XFFPubMed
TargetCytochrome P450 1B1(Homo sapiens (Human))
University of Tokyo

LigandPNGBDBM23926((E)-resveratrol | 5-[(E)-2-(4-hydroxyphenyl)etheny...)copy SMILEScopy InChI
Affinity DataKi:  800nMAssay Description:Inhibition of recombinant human CYP1B1 expressed in supersomes coexpressing NADPH-CYP reductase using 7-ethoxyresorufin as substrate after 15 mins in...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q20QWPubMed
TargetCytochrome P450 1B1(Homo sapiens (Human))
University of Tokyo

LigandPNGBDBM23926((E)-resveratrol | 5-[(E)-2-(4-hydroxyphenyl)etheny...)copy SMILEScopy InChI
Affinity DataKi:  1.12E+4nMAssay Description:Inhibition of recombinant CYP1B1 (unknown origin) expressed in supersomes coexpressing NADPH-CYP reductase using 7-ethoxyresorufin as substrate after...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q20QWPubMed
TargetCytochrome P450 1B1(Homo sapiens (Human))
University of Tokyo

LigandPNGBDBM23926((E)-resveratrol | 5-[(E)-2-(4-hydroxyphenyl)etheny...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human CYP1B1 by EROD assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930XFFPubMed
TargetCytochrome P450 1B1(Homo sapiens (Human))
University of Tokyo

LigandPNGBDBM23926((E)-resveratrol | 5-[(E)-2-(4-hydroxyphenyl)etheny...)copy SMILEScopy InChI
Affinity DataIC50: 5.50E+4nMAssay Description:Inhibition of recombinant human CYP1B1 expressed in Escherichia coli DH5aplha cells assessed as O-deethylation of ethoxyresorufin in presence of NADP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9T1MPubMed