Compile Data Set for Download or QSAR
Found 7 Enz. Inhib. hit(s) with Target = 'Cytochrome P450 1B1' and Ligand = 'BDBM50108052'
TargetCytochrome P450 1B1(Homo sapiens (Human))
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50108052(1-[(E)-2-(3,5-dimethoxyphenyl)vinyl]-2,4-dimethoxy...)copy SMILEScopy InChI
Affinity DataKi:  3nMAssay Description:Inhibition of human CYP1B1 using ethoxyresorufin as substrate preincubated for 3 mins followed by NADPH addition measured after 10 mins by EROD assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930XFFPubMed
TargetCytochrome P450 1B1(Homo sapiens (Human))
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50108052(1-[(E)-2-(3,5-dimethoxyphenyl)vinyl]-2,4-dimethoxy...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human CYP1B1 expressed in Escherichia coli DH5aplha cells assessed as O-deethylation of ethoxyresorufin in presence of NADP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9T1MPubMed
TargetCytochrome P450 1B1(Homo sapiens (Human))
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50108052(1-[(E)-2-(3,5-dimethoxyphenyl)vinyl]-2,4-dimethoxy...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human CYP1B1 expressed in Escherichia coli DH5alpha using ethoxyresorufin as substrate preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q20QWPubMed
TargetCytochrome P450 1B1(Homo sapiens (Human))
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50108052(1-[(E)-2-(3,5-dimethoxyphenyl)vinyl]-2,4-dimethoxy...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of ethoxyresorufin O-deethylation (EROD) in bicistronic bacterial membranes expressing human cytochrome P450 1B1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2668CGDPubMed
TargetCytochrome P450 1B1(Homo sapiens (Human))
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50108052(1-[(E)-2-(3,5-dimethoxyphenyl)vinyl]-2,4-dimethoxy...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human CYP1B1 expressed in Escherichia coli membranes co-expressing NADPH-P450 reductase assessed as reduction in ethoxyreso...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V1284KPubMed
TargetCytochrome P450 1B1(Homo sapiens (Human))
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50108052(1-[(E)-2-(3,5-dimethoxyphenyl)vinyl]-2,4-dimethoxy...)copy SMILEScopy InChI
In DepthDetails
TargetCytochrome P450 1B1(Homo sapiens (Human))
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50108052(1-[(E)-2-(3,5-dimethoxyphenyl)vinyl]-2,4-dimethoxy...)copy SMILEScopy InChI
Affinity DataIC50: 8.20nMMore data for this Ligand-Target Pair
In DepthDetails