Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Cytochrome P450 26A1' and Ligand = 'BDBM50158415'
TargetCytochrome P450 26A1(Homo sapiens (Human))
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50158415(4-((+/-)-(1H-imidazol-1-yl)-(E)-methylretinoate | ...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of ATRA-induced CYP26 in human T47D cell microsome assessed as ATRA metabolism using [11.12-3H]-ATRAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K64HJVPubMed
TargetCytochrome P450 26A1(Homo sapiens (Human))
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50158415(4-((+/-)-(1H-imidazol-1-yl)-(E)-methylretinoate | ...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of ATRA-induced CYP26 in human MCF7 cells assessed ATRA as metabolism using [11.12-3H]-ATRAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K64HJVPubMed
TargetCytochrome P450 26A1(Homo sapiens (Human))
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50158415(4-((+/-)-(1H-imidazol-1-yl)-(E)-methylretinoate | ...)copy SMILEScopy InChI
Affinity DataIC50: 215nMAssay Description:Inhibition of ATRA-induced CYP26 in human T47D cells assessed as ATRA metabolism using [11.12-3H]-ATRAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K64HJVPubMed