Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Cytochrome P450 26B1' and Ligand = 'BDBM50157605'
TargetCytochrome P450 26B1(Homo sapiens (Human))
University of Washington at Seattle

LigandPNGBDBM50157605(Liarozole | Liazal | R-75251 | US9963439, Liarozol...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Eighteen compounds were tested as potential inhibitors of CYP26A1 and CYP26B1. The formation of 9-cis-4-OH-RA metabolite was monitored and the percen...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FN18J2US Patent
TargetCytochrome P450 26B1(Homo sapiens (Human))
University of Washington at Seattle

LigandPNGBDBM50157605(Liarozole | Liazal | R-75251 | US9963439, Liarozol...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38VG8PubMed