Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Cytochrome P450 2D6' and Ligand = 'BDBM50410855'
TargetCytochrome P450 2D6(Homo sapiens (Human))
Universit£ Lille Nord de France

Curated by ChEMBL
LigandPNGBDBM50410855(CIN-QUIN | QUINIDEX | QUINIDINE SULFATE)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant CYP2D6 (unknown origin) using 7-methoxy-4-trifluoromethylcoumarin as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ6335PubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Universit£ Lille Nord de France

Curated by ChEMBL
LigandPNGBDBM50410855(CIN-QUIN | QUINIDEX | QUINIDINE SULFATE)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of human CYP2D6 expressed in Escherichia coli JM109More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930TZXPubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Universit£ Lille Nord de France

Curated by ChEMBL
LigandPNGBDBM50410855(CIN-QUIN | QUINIDEX | QUINIDINE SULFATE)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of recombinant human CYP2D6 preincubated for 5 mins before fluorescent substrate addition by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1MHHPubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Universit£ Lille Nord de France

Curated by ChEMBL
LigandPNGBDBM50410855(CIN-QUIN | QUINIDEX | QUINIDINE SULFATE)copy SMILEScopy InChI
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of human recombinant CYP2D6 incubated for 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2JRDPubMed