Compile Data Set for Download or QSAR
Found 6 Enz. Inhib. hit(s) with Target = 'Cytochrome P450 3A4/3A5' and Ligand = 'BDBM50538344'
TargetCytochrome P450 3A4/3A5(Homo sapiens (Human))
University of Washington

Curated by ChEMBL
LigandPNGBDBM50538344(CHEMBL4633246)copy SMILEScopy InChI
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes using midazolam as substrate preincubated for 30 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90D6ZPubMed
TargetCytochrome P450 3A4/3A5(Homo sapiens (Human))
University of Washington

Curated by ChEMBL
LigandPNGBDBM50538344(CHEMBL4633246)copy SMILEScopy InChI
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes using testosterone as substrate preincubated for 30 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90D6ZPubMed
TargetCytochrome P450 3A4/3A5(Homo sapiens (Human))
University of Washington

Curated by ChEMBL
LigandPNGBDBM50538344(CHEMBL4633246)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes using midazolam as substrate preincubated for 30 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90D6ZPubMed
TargetCytochrome P450 3A4/3A5(Homo sapiens (Human))
University of Washington

Curated by ChEMBL
LigandPNGBDBM50538344(CHEMBL4633246)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes using midazolam as substrate measured for 10 to 30 mins in presence of NADPH regenerating system by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90D6ZPubMed
TargetCytochrome P450 3A4/3A5(Homo sapiens (Human))
University of Washington

Curated by ChEMBL
LigandPNGBDBM50538344(CHEMBL4633246)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes using testosterone as substrate measured for 10 to 30 mins in presence of NADPH regenerating system ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90D6ZPubMed
TargetCytochrome P450 3A4/3A5(Homo sapiens (Human))
University of Washington

Curated by ChEMBL
LigandPNGBDBM50538344(CHEMBL4633246)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes using testosterone as substrate preincubated for 30 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90D6ZPubMed