Compile Data Set for Download or QSAR
Found 5 Enz. Inhib. hit(s) with Target = 'Cytochrome P450 3A4' and Ligand = 'BDBM222178'
TargetCytochrome P450 3A4(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM222178(Rilpivirine)copy SMILEScopy InChI
Affinity DataIC50: 2.17E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam substrate incubated for 10 mins in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6NQPPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM222178(Rilpivirine)copy SMILEScopy InChI
Affinity DataIC50: 2.17E+3nMAssay Description:Inhibition of CYP3A4M in human liver microsomes using midazolam as substrate in presence of NADPH incubated for 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057KRWPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM222178(Rilpivirine)copy SMILEScopy InChI
Affinity DataIC50: 2.17E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8RR7PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM222178(Rilpivirine)copy SMILEScopy InChI
Affinity DataIC50: 2.17E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2280CMMPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM222178(Rilpivirine)copy SMILEScopy InChI
Affinity DataIC50: 2.17E+3nMAssay Description:Inhibition of human CYP3A4 using testosterone as substrate in presence of NADPH incubated for 15 to 45 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S186CJPubMed