Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Cytochrome P450 3A4' and Ligand = 'BDBM24656'
TargetCytochrome P450 3A4(Homo sapiens (Human))
The Procter & Gamble Company

US Patent
LigandPNGBDBM24656(4-PIM | 4-Phenylimidazole | 4-phenyl-1H-imidazole ...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:A commercially available P450-GLO Assay kit (Promega Corporation, Madison Wis.) is used to screen various compounds for CYP3A4A inhibition activity. ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GF0S8JUS Patent
TargetCytochrome P450 3A4(Homo sapiens (Human))
The Procter & Gamble Company

US Patent
LigandPNGBDBM24656(4-PIM | 4-Phenylimidazole | 4-phenyl-1H-imidazole ...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Cytochrome P450 is a large and diverse group of enzymes that catalyze the oxidation of organic substances. Some members of the CYP family contribute ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22806DVUS Patent
TargetCytochrome P450 3A4(Homo sapiens (Human))
The Procter & Gamble Company

US Patent
LigandPNGBDBM24656(4-PIM | 4-Phenylimidazole | 4-phenyl-1H-imidazole ...)copy SMILEScopy InChI
Affinity DataIC50: 5.88E+4nMpH: 7.4Assay Description:All procedures were carried out under minimal light in order to prevent degradation of the retinoid samples.Microsomal preparation: one lobe of fresh...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22806DVUS Patent
TargetCytochrome P450 3A4(Homo sapiens (Human))
The Procter & Gamble Company

US Patent
LigandPNGBDBM24656(4-PIM | 4-Phenylimidazole | 4-phenyl-1H-imidazole ...)copy SMILEScopy InChI
Affinity DataIC50: 5.88E+4nMpH: 7.4 T: 2°CAssay Description:Microsomal preparation: One lobe of fresh pig liver is obtained (e.g., at about the time of slaughter from a food-processing company) and immediately...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GF0S8JUS Patent