Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Cytochrome P450 3A4' and Ligand = 'BDBM50220136'
TargetCytochrome P450 3A4(Homo sapiens (Human))
KISSEI PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM50220136(3-[2-{1-[3,5-di(trifluoromethyl)phenyl]ethoxy}-3-(...)copy SMILEScopy InChI
Affinity DataIC50: 20nMpH: 7.4 T: 2°CAssay Description:A dimethyl sulfoxide (DMSO) solution of a test compound with a concentration 1000 times higher than the evaluation concentration was prepared, and a ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HM5BGSUS PatentDrugBank
TargetCytochrome P450 3A4(Homo sapiens (Human))
KISSEI PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM50220136(3-[2-{1-[3,5-di(trifluoromethyl)phenyl]ethoxy}-3-(...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:A dimethyl sulfoxide (DMSO) solution of a test compound with a concentration 1000 times higher than the evaluation concentration was prepared, and a ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HT2RQTUS PatentDrugBank
TargetCytochrome P450 3A4(Homo sapiens (Human))
KISSEI PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM50220136(3-[2-{1-[3,5-di(trifluoromethyl)phenyl]ethoxy}-3-(...)copy SMILEScopy InChI
Affinity DataIC50: 20nMpH: 7.4 T: 2°CAssay Description:A dimethyl sulfoxide (DMSO) solution of a test compound with a concentration 1000 times higher than the evaluation concentration was prepared, and a ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W95C7CUS PatentDrugBank
TargetCytochrome P450 3A4(Homo sapiens (Human))
KISSEI PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM50220136(3-[2-{1-[3,5-di(trifluoromethyl)phenyl]ethoxy}-3-(...)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V75PubMedDrugBank