Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Cytoplasmic tyrosine-protein kinase BMX' and Ligand = 'BDBM4552'
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human BMX using poly(Glu,Tyr) 4:1 as substrate after 40 mins by scintillation counting analysis in presence of [gamma-33P-ATP]More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M96FSPubMed
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 7.90nMAssay Description:Inhibition of BMXMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z15R6PubMed
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)copy SMILEScopy InChI
Affinity DataKd:  200nMAssay Description:Binding constant for BMX kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S70PubMed