Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Cytosol aminopeptidase' and Ligand = 'BDBM50017478'
TargetCytosol aminopeptidase(Homo sapiens (Human))
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM50017478(Amastatin | CHEMBL28650 | Leu[1psi,CHOHCONH]ValVal...)copy SMILEScopy InChI
Affinity DataKi:  30nMAssay Description:Binding affinity for cytosolic leucine aminopeptidase (LAP) from porcine kidneyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P903FPubMedMMDB
TargetCytosol aminopeptidase(Homo sapiens (Human))
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM50017478(Amastatin | CHEMBL28650 | Leu[1psi,CHOHCONH]ValVal...)copy SMILEScopy InChI
Affinity DataKi:  200nMAssay Description:Effect of inhibitor structure on the slow binding inhibition of Leucine aminopeptidase was determined and the Ki was reported which is = k2/k1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q280535GPubMedMMDB
TargetCytosol aminopeptidase(Homo sapiens (Human))
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM50017478(Amastatin | CHEMBL28650 | Leu[1psi,CHOHCONH]ValVal...)copy SMILEScopy InChI
Affinity DataKi:  220nMAssay Description:Effect of inhibitor structure on the slow binding inhibition of aminopeptidase M was determined and Ki* was reported which is obtained by the equatio...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q280535GPubMedMMDB
TargetCytosol aminopeptidase(Homo sapiens (Human))
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM50017478(Amastatin | CHEMBL28650 | Leu[1psi,CHOHCONH]ValVal...)copy SMILEScopy InChI
Affinity DataKi:  2.00E+4nMAssay Description:Effect of inhibitor structure on the slow binding inhibition of aminopeptidase M was determined and the Ki was reported which is = k2/k1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q280535GPubMedMMDB