Compile Data Set for Download or QSAR
Found 12 Enz. Inhib. hit(s) with Target = 'D(2) dopamine receptor' and Ligand = 'BDBM50020217'
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of Amsterdam

Curated by ChEMBL
LigandPNGBDBM50020217((4aR,10bR)-4-propyl-3,4,4a,5,6,10b-hexahydro-2H-na...)copy SMILEScopy InChI
Affinity DataKi:  0.450nMAssay Description:Displacement of [3H]spiperone from high-affinity state of human dopamine D2L receptor transfected in HEK293 cells after 2 hrs by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8VQDPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of Amsterdam

Curated by ChEMBL
LigandPNGBDBM50020217((4aR,10bR)-4-propyl-3,4,4a,5,6,10b-hexahydro-2H-na...)copy SMILEScopy InChI
Affinity DataKi:  0.450nMAssay Description:Displacement of [3H]spiperone from high-affinity state of human dopamine D2L receptor transfected in HEK293 cells after 2 hrs by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8VQDPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of Amsterdam

Curated by ChEMBL
LigandPNGBDBM50020217((4aR,10bR)-4-propyl-3,4,4a,5,6,10b-hexahydro-2H-na...)copy SMILEScopy InChI
Affinity DataKi:  1.5nMAssay Description:Binding affinity to high-affinity state of D2L receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8VQDPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of Amsterdam

Curated by ChEMBL
LigandPNGBDBM50020217((4aR,10bR)-4-propyl-3,4,4a,5,6,10b-hexahydro-2H-na...)copy SMILEScopy InChI
Affinity DataKi:  6.20nMAssay Description:Human Dopamine receptor D2L affinities to determine agonist activity, using [3H]spip as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X067R1PubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of Amsterdam

Curated by ChEMBL
LigandPNGBDBM50020217((4aR,10bR)-4-propyl-3,4,4a,5,6,10b-hexahydro-2H-na...)copy SMILEScopy InChI
Affinity DataKi:  6.31nMAssay Description:Agonistic activity at DRD2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7X7CPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of Amsterdam

Curated by ChEMBL
LigandPNGBDBM50020217((4aR,10bR)-4-propyl-3,4,4a,5,6,10b-hexahydro-2H-na...)copy SMILEScopy InChI
Affinity DataKi:  8.5nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C827SRPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of Amsterdam

Curated by ChEMBL
LigandPNGBDBM50020217((4aR,10bR)-4-propyl-3,4,4a,5,6,10b-hexahydro-2H-na...)copy SMILEScopy InChI
Affinity DataKi:  17nMAssay Description:Displacement of [3H]spiperone from low-affinity state of human dopamine D2S receptor transfected in HEK293 cells after 2 hrs by scintillation countin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8VQDPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of Amsterdam

Curated by ChEMBL
LigandPNGBDBM50020217((4aR,10bR)-4-propyl-3,4,4a,5,6,10b-hexahydro-2H-na...)copy SMILEScopy InChI
Affinity DataKi:  19nMAssay Description:Displacement of [3H]spiperone from low-affinity state of human dopamine D2S receptor transfected in HEK293 cells after 2 hrs by scintillation countin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8VQDPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of Amsterdam

Curated by ChEMBL
LigandPNGBDBM50020217((4aR,10bR)-4-propyl-3,4,4a,5,6,10b-hexahydro-2H-na...)copy SMILEScopy InChI
Affinity DataKi:  21nMAssay Description:Displacement of [3H]spiperone from low-affinity state of human dopamine D2L receptor transfected in HEK293 cells after 2 hrs by scintillation countin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8VQDPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of Amsterdam

Curated by ChEMBL
LigandPNGBDBM50020217((4aR,10bR)-4-propyl-3,4,4a,5,6,10b-hexahydro-2H-na...)copy SMILEScopy InChI
Affinity DataKi:  21nMAssay Description:Displacement of [3H]spiperone from low-affinity state of human dopamine D2L receptor transfected in HEK293 cells after 2 hrs by scintillation countin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8VQDPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of Amsterdam

Curated by ChEMBL
LigandPNGBDBM50020217((4aR,10bR)-4-propyl-3,4,4a,5,6,10b-hexahydro-2H-na...)copy SMILEScopy InChI
Affinity DataKi:  147nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8QBHPubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
State University of Groningen

Curated by ChEMBL
LigandPNGBDBM50020217((4aR,10bR)-4-propyl-3,4,4a,5,6,10b-hexahydro-2H-na...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Potency to displace the specific in vitro binding of [3H]DP-5,6-ADTN to rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22R3S82PubMed