Compile Data Set for Download or QSAR
Found 8 Enz. Inhib. hit(s) with Target = 'D(2) dopamine receptor' and Ligand = 'BDBM50041959'
TargetD(2) dopamine receptor(Homo sapiens (Human))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50041959(((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...)copy SMILEScopy InChI
Affinity DataKi:  14nMAssay Description:Compound was tested for agonistic activity against D2 receptor from cloned CHO cells, used [3H]U-86170 as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TD9Z06PubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50041959(((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...)copy SMILEScopy InChI
Affinity DataKi:  120nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4TKGPubMed
TargetD(2) dopamine receptor(BOVINE)
University of Göteborg

Curated by ChEMBL
LigandPNGBDBM50041959(((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...)copy SMILEScopy InChI
Affinity DataKi:  145nMAssay Description:Binding towards Dopamine receptor D2 expressed in CHO-K1 cells using [3H]-U-86,170More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VH5MWJPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50041959(((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...)copy SMILEScopy InChI
Affinity DataKi:  145nMAssay Description:Binding affinity of the compound was measured at cloned mammalian dopamine D2 receptor expressed in CHO-K1 cells (using [3H]-U-86,170)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SX6D5J
TargetD(2) dopamine receptor(BOVINE)
University of Göteborg

Curated by ChEMBL
LigandPNGBDBM50041959(((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...)copy SMILEScopy InChI
Affinity DataKi:  158nMAssay Description:Binding towards Dopamine receptor D2 expressed in CHO-K1 cells using [3H]-U-86,170More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VH5MWJPubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50041959(((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...)copy SMILEScopy InChI
Affinity DataKi:  179nMAssay Description:Compound was tested for antagonistic activity against D2 receptor from rat striatum, used [3H]raclopride as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TD9Z06PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50041959(((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...)copy SMILEScopy InChI
Affinity DataKi:  300nMAssay Description:Binding towards Dopamine receptor D2 expressed in CHO-K1 cells using [3H]-U-86,170More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VH5MWJPubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50041959(((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...)copy SMILEScopy InChI
Affinity DataKi:  530nMAssay Description:Binding towards Dopamine receptor D2 using [3H]-spiperone from rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VH5MWJPubMed