Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'D(2) dopamine receptor' and Ligand = 'BDBM50061654'
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50061654(2-(3,4-Dihydro-1H-isoquinolin-2-ylmethyl)-chroman-...)copy SMILEScopy InChI
Affinity DataKi:  0.600nMAssay Description:In vitro binding affinity to rat striatal Dopamine receptor D2 was determined using the agonist [3H]quinpirole to label the high affinity state (D2 h...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KP82TDPubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50061654(2-(3,4-Dihydro-1H-isoquinolin-2-ylmethyl)-chroman-...)copy SMILEScopy InChI
Affinity DataKi:  3.20nMAssay Description:In vitro binding affinity to rat striatal Dopamine receptor D2 was determined using the antagonist [3H]spiperone + GTP to label the low affinity stat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KP82TDPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50061654(2-(3,4-Dihydro-1H-isoquinolin-2-ylmethyl)-chroman-...)copy SMILEScopy InChI
Affinity DataKi:  4.30nMAssay Description:Compound was tested to inhibit Dopa accumulation in to Dopamine receptor D2 at 10 mg/kg, scMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KP82TDPubMed