Compile Data Set for Download or QSAR
Found 11 Enz. Inhib. hit(s) with Target = 'D(3) dopamine receptor' and Ligand = 'BDBM50020680'
TargetD(3) dopamine receptor(Homo sapiens (Human))
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50020680(4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-...)copy SMILEScopy InChI
Affinity DataKi:  19nMAssay Description:Binding affinity towards Dopamine receptor D3 by displacement of [3H]-(+)-7-OH-DPAT.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29P30R9PubMed
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50020680(4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-...)copy SMILEScopy InChI
Affinity DataKi:  29.3nMAssay Description:Displacement of [3H]spiperone from rat D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37WJ9PubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50020680(4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-...)copy SMILEScopy InChI
Affinity DataKi:  36.3nMAssay Description:Displacement of [3H]spiperone form human cloned dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28W3FH9PubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50020680(4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-...)copy SMILEScopy InChI
Affinity DataKi:  37.1nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1PM2PubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50020680(4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-...)copy SMILEScopy InChI
Affinity DataKi:  37.1nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7N2FPubMed
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50020680(4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-...)copy SMILEScopy InChI
Affinity DataIC50: 107nMAssay Description:Displacement of [3H]nemonapride from Rattus norvegicus (rat) wild type dopamine D3 receptor transfected in african green monkey COS7 cells after 1 hr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2377CM7
TargetD(3) dopamine receptor(Homo sapiens (Human))
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50020680(4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-...)copy SMILEScopy InChI
Affinity DataEC50:  100nMAssay Description:Inhibitory activity against constrictor response to electrical stimulation in the isolated perfused rabbit ear artery(REA) expressing dopamine recept...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CC12WPPubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50020680(4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-...)copy SMILEScopy InChI
Affinity DataEC50:  10.3nMAssay Description:Agonist activity at human dopamine D3 receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37WJ9PubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50020680(4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-...)copy SMILEScopy InChI
Affinity DataEC50:  19.2nMAssay Description:Agonist activity at human dopamine D3 receptor expressed in mouse AtT-20 cells assessed as stimulation of [35S]GTPgamma bindingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29023VMPubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50020680(4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-...)copy SMILEScopy InChI
Affinity DataEC50:  4nMAssay Description:Agonist activity at human recombinant dopamine D3 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3CQ5PubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50020680(4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-...)copy SMILEScopy InChI
Affinity DataEC50:  10.3nMAssay Description:Agonist activity at human dopamine D3 receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K28QZPubMed