Compile Data Set for Download or QSAR
Found 22 Enz. Inhib. hit(s) with Target = 'D(4) dopamine receptor' and Ligand = 'BDBM55121'
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM55121(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)copy SMILEScopy InChI
Affinity DataKi:  1.20nMAssay Description:Binding Affinity was tested on the high affinity site of Dopamine receptor D4.4More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6CXPPubMedDrugBank
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM55121(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)copy SMILEScopy InChI
Affinity DataKi:  6.20nMAssay Description:Displacement of [3H]spiperone from human D4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN08TCPubMedDrugBank
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM55121(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)copy SMILEScopy InChI
Affinity DataKi:  42.9nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K48SDPubMedDrugBank
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM55121(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)copy SMILEScopy InChI
Affinity DataKi:  57nMAssay Description:Binding Affinity was tested on relative proportion of High Affinity Site of Dopamine receptor D4.4More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6CXPPubMedDrugBank
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM55121(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)copy SMILEScopy InChI
Affinity DataKi:  62nMAssay Description:Binding Affinity was tested on low Affinity Site of Dopamine receptor D4.4More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6CXPPubMedDrugBank
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM55121(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)copy SMILEScopy InChI
Affinity DataKi:  97nMAssay Description:Binding Affinity was determined in the presence of 100 micro M Gpp(NH)p for decoupling of the ternary complex of Compound to Dopamine receptor D4.4More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6CXPPubMedDrugBank
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM55121(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)copy SMILEScopy InChI
Affinity DataKi:  180nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CC0Z63PubMedDrugBank
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM55121(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)copy SMILEScopy InChI
Affinity DataKi:  407nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CC0Z63PubMedDrugBank
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM55121(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)copy SMILEScopy InChI
Affinity DataKi:  3.31E+3nMAssay Description:Inhibitory constant for [3H]YM-09151-2 binding to Dopamine receptor D2-like in porcine striatal membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR4XW2PubMedDrugBank
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM55121(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)copy SMILEScopy InChI
Affinity DataEC50:  269nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7TTCPubMedDrugBank
TargetD(4) dopamine receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM55121(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)copy SMILEScopy InChI
Affinity DataEC50:  2.40nMAssay Description:In vitro effective concentration tested on HEK293 cells co-transfected with rat Dopamine receptor D4 using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B3225PubMed
TargetD(4) dopamine receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM55121(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)copy SMILEScopy InChI
Affinity DataEC50:  2.70nMAssay Description:In vitro effective concentration tested on HEK293 cells co-transfected with ferret Dopamine receptor D4 using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B3225PubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM55121(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)copy SMILEScopy InChI
Affinity DataEC50:  2.20nMAssay Description:In vitro effective concentration tested on HEK293 cells co-transfected with human Dopamine receptor D4 using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B3225PubMedDrugBank
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM55121(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)copy SMILEScopy InChI
Affinity DataEC50:  10nMAssay Description:Binding affinity to human cloned dopamine D4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3M92PubMedDrugBank
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM55121(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)copy SMILEScopy InChI
Affinity DataEC50:  12nMAssay Description:Agonist activity at human SP/Myc epitope-tagged dopamine D4 receptor expressed in HEK293T cells assessed as RLuc8-fused Galphai1 activation after 2 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K2C2PPubMedDrugBank
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM55121(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)copy SMILEScopy InChI
Affinity DataEC50:  91nMAssay Description:Agonist activity at human SP/Myc epitope-tagged dopamine D4 receptor expressed in HEK293T cells assessed as mVenus-fused beta-arrestin2 recruitment a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K2C2PPubMedDrugBank
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM55121(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)copy SMILEScopy InChI
Affinity DataEC50:  1.80nMAssay Description:Agonist activity at D4R (unknown origin) expressed in HEK293 cells assessed as effect on cAMP accumulation incubated for 10 mins by Gi-cAMP Glosensor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9FKVPubMedDrugBank
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM55121(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)copy SMILEScopy InChI
Affinity DataEC50:  15nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7TTCPubMedDrugBank
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM55121(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)copy SMILEScopy InChI
Affinity DataEC50:  21nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7TTCPubMedDrugBank
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM55121(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)copy SMILEScopy InChI
Affinity DataEC50:  2.70nMAssay Description:Agonist activity at ferret D4 receptor in HEK293 cells coexpressing Galphaqo5 by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X28MMPubMedDrugBank
TargetD(4) dopamine receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM55121(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)copy SMILEScopy InChI
Affinity DataEC50:  2.40nMAssay Description:Agonist activity at rat D4 receptor in HEK293 cells coexpressing Galphaqo5 by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X28MMPubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM55121(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)copy SMILEScopy InChI
Affinity DataEC50:  2.20nMAssay Description:Agonist activity at human D4.4 receptor in HEK293 cells coexpressing Galphaqo5 by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X28MMPubMedDrugBank