Found 4 Enz. Inhib. hit(s) with Target = 'D-3-phosphoglycerate dehydrogenase' and Ligand = 'BDBM50519131' TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG
Curated by ChEMBL
Boehringer Ingelheim RCV GmbH & Co. KG
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of PHGDH in human MDA-MB-468 cells assessed as reduction in [13C]-serine incubated for 1 hr using [13C]glucose as substrate by LC-MS/MS an...More data for this Ligand-Target Pair
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG
Curated by ChEMBL
Boehringer Ingelheim RCV GmbH & Co. KG
Curated by ChEMBL
Affinity DataIC50: 169nMAssay Description:Compounds are dispensed onto assay plates (black, low volume, flat bottom 384 well, Corning) using an Access Labcyte Workstation with the Labcyte Ech...More data for this Ligand-Target Pair
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG
Curated by ChEMBL
Boehringer Ingelheim RCV GmbH & Co. KG
Curated by ChEMBL
Affinity DataIC50: 258nMAssay Description:Compounds are dispensed onto assay plates (black, low volume, flat bottom 384 well, Corning) using an Access Labcyte Workstation with the Labcyte Ech...More data for this Ligand-Target Pair
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG
Curated by ChEMBL
Boehringer Ingelheim RCV GmbH & Co. KG
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of PHGDH in human MDA-MB-468 cells assessed as reduction in [13C]-serine incubated for 72 hrs using [13C]glucose as substrate by LC-MS/MS ...More data for this Ligand-Target Pair
