Compile Data Set for Download or QSAR
Found 11 Enz. Inhib. hit(s) with Target = 'D-amino-acid oxidase' and Ligand = 'BDBM50431085'
TargetD-amino-acid oxidase(Rattus norvegicus (rat))
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50431085(CHEMBL2338801 | US10202399, Example 12 | US1046366...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of rat full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2QPZPubMed
TargetD-amino-acid oxidase(Mus musculus)
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50431085(CHEMBL2338801 | US10202399, Example 12 | US1046366...)copy SMILEScopy InChI
Affinity DataIC50: 5.90nMAssay Description:Inhibition of mouse full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2QPZPubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50431085(CHEMBL2338801 | US10202399, Example 12 | US1046366...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant DAAO after 30 mins by plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2QPZPubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50431085(CHEMBL2338801 | US10202399, Example 12 | US1046366...)copy SMILEScopy InChI
Affinity DataIC50: 12nMpH: 7.5 T: 2°CAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29G5KKSUS Patent
TargetD-amino-acid oxidase(Homo sapiens (Human))
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50431085(CHEMBL2338801 | US10202399, Example 12 | US1046366...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2542QQDUS Patent
TargetD-amino-acid oxidase(Homo sapiens (Human))
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50431085(CHEMBL2338801 | US10202399, Example 12 | US1046366...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2 which c...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2BXGUS Patent
TargetD-amino-acid oxidase(Homo sapiens (Human))
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50431085(CHEMBL2338801 | US10202399, Example 12 | US1046366...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Human DAAO enzyme was supplied by the Takeda Pharmaceutical Company (Osaka) and each batch was tested and used at concentrations giving comparable le...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6GCRUS Patent
TargetD-amino-acid oxidase(Homo sapiens (Human))
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50431085(CHEMBL2338801 | US10202399, Example 12 | US1046366...)copy SMILEScopy InChI
Affinity DataIC50: 19nMpH: 7.4 T: 2°CAssay Description:Human DAAO enzyme was supplied by the Takeda Pharmaceutical Company (Osaka) and each batch was tested and used at concentrations giving comparable le...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RF5SW0US Patent
TargetD-amino-acid oxidase(Homo sapiens (Human))
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50431085(CHEMBL2338801 | US10202399, Example 12 | US1046366...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Human DAAO enzyme was supplied by the Takeda Pharmaceutical Company (Osaka) and each batch was tested and used at concentrations giving comparable le...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F76FWCUS Patent
TargetD-amino-acid oxidase(Homo sapiens (Human))
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50431085(CHEMBL2338801 | US10202399, Example 12 | US1046366...)copy SMILEScopy InChI
Affinity DataIC50: 27nMpH: 7.5 T: 2°CAssay Description:This test was performed by partially modifying the method of Philip et. al. (J. Biomol. Screen. Vol. 11, pp 481-487, 2006). HEK293 cells that stably ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29G5KKSUS Patent
TargetD-amino-acid oxidase(Homo sapiens (Human))
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50431085(CHEMBL2338801 | US10202399, Example 12 | US1046366...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of human full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2QPZPubMed