Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'DNA (cytosine-5)-methyltransferase 1' and Ligand = 'BDBM50457746'
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
WuXi Apptec (Tianjin) Co. Ltd.

Curated by ChEMBL
LigandPNGBDBM50457746(CHEMBL4208004)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of human DNMT1 using polydeoxyinosine polydeoxycytosine DNA as substrate after 15 mins in presence of SAM by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP05CMPubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
WuXi Apptec (Tianjin) Co. Ltd.

Curated by ChEMBL
LigandPNGBDBM50457746(CHEMBL4208004)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of human DNMT1 enzyme using polydeoxy-inosine polydeoxy-cytosine DNA as substrate incubated for 15 mins in presence of SAM by TR-FRET assa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9V8VPubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
WuXi Apptec (Tianjin) Co. Ltd.

Curated by ChEMBL
LigandPNGBDBM50457746(CHEMBL4208004)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of DNMT1 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9V8VPubMed